Diflorasone Diacetate CAS 33564-31-7
| CAS No. | 33564-31-7 |
| Molecular Formula | C26H32F2O7 |
| Molecular Weight | 494.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Diflorasone Diacetate (CAS 33564-31-7), molecular formula C26H32F2O7 and molecular weight 494.52 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Diflorasone Diacetate (C26H32F2O7) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H32F2O7 |
| Molecular Weight | 494.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | F-containing |
Related Diflorasone Standards
- Diflorasone Impurity 5 (CAS CATO-C4X-24805)
- Diflorasone 17-propionate (CAS 924726-89-6)
- Diflorasone 21-Propionate (CAS 541502-98-1)
- Diflorasone impurity 6 (CAS CATO-C4X-24806)
- Diflorasone 21-acetate (CAS 3826-17-3)
- Diflorasone impurity 4 (CAS CATO-C4X-24804)
- Diflorasone impurity 3 (CAS CATO-C4X-24803)
- Diflorasone (CAS 2557-49-5)
Recommended Standards
- Fluocinolone Acetonide EP Impurity M (CAS 356-12-7)
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- Fluocinonide Impurity 2 (CAS 67438-37-3)
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