2-(4-Chlorophenyl)-2-morpholinoacetonitrile CAS 33599-26-7
| CAS No. | 33599-26-7 |
| Molecular Formula | C12H13ClN2O |
| Molecular Weight | 236.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 236.70 g/mol gives 2-(4-Chlorophenyl)-2-morpholinoacetonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(4-Chlorophenyl)-2-morpholinoacetonitrile (CAS 33599-26-7) is a high-purity analytical reference standard with the molecular formula C12H13ClN2O and a molecular weight of 236.70 g/mol.
The molecular framework of 2-(4-Chlorophenyl)-2-morpholinoacetonitrile (C12H13ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(4-Chlorophenyl)-2-morpholinoacetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13ClN2O |
| Molecular Weight | 236.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 2-Chloro-3-isopropyl-7-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 2137625-52-4)
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- 1,2,3-Trimethoxydibenzo[b,d]furan (CAS 88256-08-0)
- 3-(1-Methylpiperidin-2-yl)-2-(methylthio)pyridine (CAS 1352511-85-3)
- (S)-N,N-Diethylpregabalinamide (CAS 1094517-97-1)
- Ethyl 3-chloro-5H,6H,7H,8H-pyrido[4,3-c]pyridazine-6-carboxylate (CAS 39715-99-6)
- 4,6,7,8-Tetrahydro-1H-thiopyrano[3,2-d]pyrimidin-4-ol (CAS 111896-66-3)
- Methyl 3-phenylpyrrolidine-2-carboxylate (CAS 771452-35-8)
- (E)-1-(4-(5-Methyl-1,3,4-thiadiazol-2-yl)piperidin-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one (CAS 1396889-86-3)
- Rosuvastatin Impurity 184 (CAS CATO-C4X-1169184)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
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