3-Amino-N-(4-ethoxyphenyl)-4,6-diphenylthieno[2,3-b]pyridine-2-carboxamide CAS 336180-44-0
| CAS No. | 336180-44-0 |
| Molecular Formula | C28H23N3O2S |
| Molecular Weight | 465.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Amino-N-(4-ethoxyphenyl)-4,6-diphenylthieno[2,3-b]pyridine-2-carboxamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Amino-N-(4-ethoxyphenyl)-4,6-diphenylthieno[2,3-b]pyridine-2-carboxamide (CAS 336180-44-0), molecular formula C28H23N3O2S and molecular weight 465.57 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-Amino-N-(4-ethoxyphenyl)-4,6-diphenylthieno[2,3-b]pyridine-2-carboxamide (C28H23N3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 19.0, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 465.57 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H23N3O2S |
| Molecular Weight | 465.57 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-4-(4-methoxyphenyl)-N-phenyl-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 333777-86-9)
- 3-Amino-N-(2-methoxyphenyl)-4-phenyl-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 332171-23-0)
- 8-((5'-Amino-2'-Methyl-3'-Thiapentyl)Amino)-6-Methoxy-4-Methyl-5-((3-Trifluoromethyl)Phenoxy)Quinoline (CAS 98586-87-9)
- (S)-2-Amino-6-(Boc-amino)-N-(2,2-diethoxyethyl)-N-phenethylhexanamide (CAS 1222068-60-1)
- 4-((2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)thio)-1-(4-fluorophenyl)butan-1-one (CAS 88010-97-3)
- 2-(2-Amino-3-methylbutanamido)acetic acid (CAS 14297-28-0)
- (5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4-hydroxy-4,5-dihydrofuran-2-yl)methyl tetrahydrogen triphosphate (CAS 2514801-98-8)
- 2-Amino-5-chloro-α-(cyclopropyl-d4-ethynyl)-4-isopropylsilyloxy-α-(trifluoromethyl)benzenemethanol (CAS 1216572-03-0)
Recommended Standards
- Edoxaban Impurity 95 (CAS 480450-85-9)
- Methyl 2-({[4-(benzyloxy)phenyl]methyl}(2,2-diphenylethyl)amino)acetate (CAS 1186194-54-6)
- 2-((3-Cyano-6-phenyl-4-(p-tolyl)pyridin-2-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 332128-10-6)
- (3-((4-(tert-Butoxy)phenoxy)methyl)-3,4-dihydroisoquinolin-2(1H)-yl)(naphthalen-1-yl)methanone (CAS 1380548-02-6)
- 4-((1-Isopropylpiperidin-4-yl)oxy)pyridin-3-amine (CAS 1710853-65-8)
- 2,6-Dichloro-4-(3-(fluoromethyl)bicyclo[1.1.1]Pentan-1-yl)pyridine (CAS 2201290-14-2)
- 3-iodo-4-methoxy-benzoic acid hydrazide 314763-97-8 SC-42091 (CAS 314763-97-8)
- [4-(difluoromethoxy)-3-methoxyphenyl]acetonitrile (CAS 852851-91-3)
- 4-(4-Ethylphenyl)-3,4-dihydrofuro[3,4-d]pyrimidine-2,5(1H,7H)-dione (CAS 1707603-59-5)
- (2S)-N'-Nitrosonornicotine-d4 (CAS 1426174-36-8)
- 2-(2-(3,4-Dimethoxyphenyl)acetyl)-N-methylhydrazine-1-carbothioamide (CAS 329779-69-3)
- N-Methyl Paroxetine Dimer (CAS CATO-C4X-103573)
- n-(4-Methyl-3-(1h-tetrazol-1-yl)phenyl)propionamide (CAS 1185168-71-1)
- [Glu]17-Semaglutide (CAS CATO-CPTD788604)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com