2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetonitrile CAS 33630-46-5

Purity 97%+In StockPharmaceutical Standards
CAS No.33630-46-5
Molecular FormulaC9H9NO3
Molecular Weight179.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetonitrile CAS 33630-46-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 179.17 g/mol gives 2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetonitrile (CAS 33630-46-5), a certified reference material (molecular formula C9H9NO3, MW 179.17 g/mol) for analytical method development and quality control.

The molecular framework of 2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetonitrile (C9H9NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H9NO3
Molecular Weight179.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1966
Nitrogen Atoms1

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