Thiazole-4-carboxaldehyde CAS 3364-80-5
| CAS No. | 3364-80-5 |
| Molecular Formula | C4H3NOS |
| Molecular Weight | 113.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Thiazole-4-carboxaldehyde (CAS 3364-80-5), molecular formula C4H3NOS and molecular weight 113.14 g/mol, is a CATO reference standard with documented purity and traceability.
Thiazole-4-carboxaldehyde (C4H3NOS) contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H3NOS |
| Molecular Weight | 113.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Thiazole Standards
- Thiazole-2,4-diamine (CAS 67355-26-4)
- Thiazole-2,5-diamine (CAS 95511-80-1)
- 1,2-Thiazole-3-carbonitrile (CAS 1452-17-1)
- Thiazole-5-carbonitrile (CAS 25742-12-5)
- Thiazole-2,4-diol (CAS 62326-99-2)
- 1,2-thiazole-5-carbaldehyde (CAS 5242-57-9)
- Thiazole-5(4H)-thione (CAS 106986-37-2)
- Thiazole-5-thiol (CAS 120405-09-6)
Recommended Standards
- Isothiazole-4-carbaldehyde (CAS 822-54-8)
- 2-Fluorotoluene-α,α,α-d3 (CAS 25319-49-7)
- Isothiazole-3-carbaldehyde (CAS 34490-97-6)
- 3-Fluorotoluene-α,α,α-d3 (CAS 4202-92-0)
- 6,6-Dimethoxy-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine (CAS 2138565-43-0)
- 1,3-Bis((diphenylphosphino)methyl)benzene (CAS 89756-88-7)
- (S)-2-(2-Fluoro-4-methoxyphenyl)pyrrolidine (CAS 1213101-67-7)
- 2-(7H-pyrrolo[2,3-b]pyridin-7-yl)acetic acid (CAS 807269-92-7)
- [2-Amino-4-(4-ethoxy-phenyl)-thiazol-5-yl]-acetic acid (CAS 1019111-18-2)
- 1-[3-(aminomethyl)phenyl]piperidin-2-one hydrochloride (CAS 1193390-49-6)
- 1-(6-Oxa-3-azabicyclo[3.1.0]hexan-3-yl)ethan-1-one (CAS 31865-21-1)
- 5-(4-(Dimethylamino)phenyl)-4,4-dimethyl-4,5-dihydroisoxazol-5-ol (CAS 61184-65-4)
- (R)-3-((tert-Butyldimethylsilyl)oxy)butanal (CAS 72150-39-1)
- Semaglutide Impurity 137 (x TFA Salt) (CAS CATO-C4X-2226137)
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