5-Chlorobenzo[d]oxazole-2-carbonitrile CAS 33652-89-0
| CAS No. | 33652-89-0 |
| Molecular Formula | C8H3ClN2O |
| Molecular Weight | 178.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Chlorobenzo[d]oxazole-2-carbonitrile (CAS 33652-89-0), a certified reference material (molecular formula C8H3ClN2O, MW 178.58 g/mol) for analytical method development and quality control.
5-Chlorobenzo[d]oxazole-2-carbonitrile (C8H3ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H3ClN2O |
| Molecular Weight | 178.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorobenzo Standards
- 2-Chlorobenzo[d]oxazole-5-carbonitrile (CAS 114997-92-1)
- 2-Chlorobenzo[d]oxazole-4-carbonitrile (CAS 1372188-34-5)
- 2-Chlorobenzo[d]oxazole-6-carbonitrile (CAS 1397706-42-1)
- 6-Chlorobenzo[d]isoxazole-3-carbonitrile (CAS 52046-83-0)
- 5-Chlorobenzo[d][1,2,3]triazin-4(3H)-one (CAS 1008742-24-2)
- 2-Chlorobenzo[d]oxazole-5-carbaldehyde (CAS 1648730-18-0)
- 2-Chlorobenzo[d]oxazole-6-carbaldehyde (CAS 1780575-73-6)
- 2-Chlorobenzo[d]oxazole-7-carbaldehyde (CAS 1803803-30-6)
Recommended Standards
- 5-Chloro-6-methylpyrazine-2,3-dicarbonitrile (CAS 72126-54-6)
- 5-chloro-2-isocyanatobenzonitrile (CAS 64411-72-9)
- 7-Chlorofuro[3,2-b]pyridine-2-carbonitrile (CAS 220992-47-2)
- 5-Chloro-[1,2,4]triazolo[4,3-a]pyridine-3-carbonitrile (CAS 66999-73-3)
- Clenbuterol EP Impurity B (CAS 69708-36-7)
- 3-(6-Bromo-2-oxobenzo[d]thiazol-3(2H)-yl)propanoic acid (CAS 1192805-99-4)
- 4-Chloro-2-(methylsulfonyl)thieno[2,3-d]pyrimidine (CAS 598298-11-4)
- Veratramine (CAS 60-70-8)
- 1-Amino-2,2,5,5-tetramethylhexan-3-ol (CAS 1509079-04-2)
- SIMMONDSIN (CAS 51771-52-9)
- 11,11,12,12-Tetracyanonaphtho-2,6-quinodimethane (CAS 6251-01-0)
- 4-(Benzenesulfonyl)-1,3-dimethyl-2,3-dihydro-1H-imidazol-2-one (CAS 185011-09-0)
- Cefmetazole Impurity 43 (CAS CATO-C4X-150743)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com