Methyl 1-benzhydrylazetidine-2-carboxylate CAS 33667-52-6

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Methyl 1-benzhydrylazetidine-2-carboxylate (CAS 33667-52-6) is a high-purity analytical reference standard with the molecular formula C18H19NO2 and a molecular weight of 281.35 g/mol.

The molecular framework of Methyl 1-benzhydrylazetidine-2-carboxylate (C18H19NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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