2,2-Dimethyl-5-oxopyrrolidine-3-carboxylic acid CAS 33712-86-6
| CAS No. | 33712-86-6 |
| Molecular Formula | C7H11NO3 |
| Molecular Weight | 157.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,2-Dimethyl-5-oxopyrrolidine-3-carboxylic acid (CAS 33712-86-6) is a high-purity analytical reference standard with the molecular formula C7H11NO3 and a molecular weight of 157.17 g/mol.
2,2-Dimethyl-5-oxopyrrolidine-3-carboxylic acid (C7H11NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H11NO3 |
| Molecular Weight | 157.17 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
Related Dimethyl Standards
- (S)-4,4-dimethyl-5-oxopyrrolidine-2-carboxylic acid (CAS 1217832-12-6)
- 3,3-dimethyl-5-oxopyrrolidine-2-carboxylic acid (CAS 141978-97-4)
- 5,5-Dimethyl-3-oxopyrazolidine-1-carboxamide (CAS 174470-58-7)
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- N,5-Dimethyl-2-oxoimidazolidine-1-carboxamide (CAS 88408-07-5)
Recommended Standards
- 2-(Pyridin-4-yl)pyrimidine (CAS 74801-33-5)
- 2,3-dihydro-3-oxo-1H-indene-4-carbonitrile (CAS 215362-26-8)
- 2-(Pyridin-3-yl)pyrimidine (CAS 73082-74-3)
- 2,5-Pyridinediacetonitrile (CAS 46126-83-4)
- N,N,2,6-Tetramethylpyrimidin-4-amine hydrochloride (CAS 74091-50-2)
- Benzoic acid, 4-formyl-2-methyl-, ethyl ester (CAS 71441-11-7)
- Methyl 1-amino-6-fluoro-2,3-dihydro-1H-indene-4-carboxylate (CAS 1824291-58-8)
- Ethyl 2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 667920-89-0)
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