2-((3-Cyano-4,6-diphenylpyridin-2-yl)thio)-N-(2-hydroxyphenyl)acetamide CAS 337354-82-2
| CAS No. | 337354-82-2 |
| Molecular Formula | C26H19N3O2S |
| Molecular Weight | 437.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-((3-Cyano-4,6-diphenylpyridin-2-yl)thio)-N-(2-hydroxyphenyl)acetamide (CAS 337354-82-2), molecular formula C26H19N3O2S and molecular weight 437.51 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-((3-Cyano-4,6-diphenylpyridin-2-yl)thio)-N-(2-hydroxyphenyl)acetamide (C26H19N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H19N3O2S |
| Molecular Weight | 437.51 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cyano Standards
- Methyl 2-(2-cyano-3-(4-(diethylamino)phenyl)acrylamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 379714-54-2)
- 2-{[3-cyano-4-(trifluoromethyl)-5H,6H,7H,8H,9H,10H-cycloocta[b]pyridin-2-yl]sulfanyl}-N-(4-fluorophenyl)acetamide (CAS 626228-71-5)
- 2-{[3-cyano-4-(trifluoromethyl)-5H,6H,7H-cyclopenta[b]pyridin-2-yl]sulfanyl}-N-(2,4-dimethoxyphenyl)acetamide (CAS 626227-27-8)
- 3-Cyano-6-(2,4-dichlorophenyl)pyridin-2-yl 2,6-dichlorobenzoate (CAS 400075-78-7)
- N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-2-((3-cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)thio)acetamide (CAS 443120-82-9)
- 2-((7-Cyano-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridin-6-yl)thio)-N-(3,4-dimethoxyphenethyl)acetamide (CAS 728001-60-3)
- N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-2-((3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 445383-16-4)
- Ethyl 2-cyano-3-(3-methoxy-4-(2-((2-methyl-5-nitrophenyl)amino)-2-oxoethoxy)phenyl)acrylate (CAS 334497-35-7)
Recommended Standards
- 1-[2-(3-Benzyl-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl)-acetyl]-piperidine-4-carboxylic acid (CAS 735336-28-4)
- 2-(4-Butoxyphenyl)-5-(2,5-dimethoxybenzylidene)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 618073-64-6)
- [4-[[5-Fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-ly]-2-pyrimidinyl]amino]phenyl][(3S)-3-(methylamino)-1-pyrrolidinyl]methanone (CAS 924641-59-8)
- 2,4-Dimethyl 3-{2-[4-(4-methoxyphenyl)piperazin-1-yl]acetyl}-1,3-thiazolidine-2,4-dicarboxylate (CAS 294849-09-5)
- (5aR,10bS)-2-Phenyl-5a,10b-dihydro-4H,6H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-2-iumtetrafluoroborate (CAS 925706-36-1)
- (S)-2-Amino-3-(1H-pyrrol-2-yl)propanoic acid (CAS 698342-24-4)
- 2,4-Diaminopyrimidine-5-boronic acid pinacol ester, 97% (CAS 944401-61-0)
- N1-(5-Isopropyl-1,3,4-thiadiazol-2-yl)-N4-phenylsuccinamide (CAS 107811-36-9)
- 2-Amino-5-bromo-6-methylnicotinic acid (CAS 1781727-71-6)
- 7-Methyl-2-trifluoromethyl-[1,2,4]triazolo[1,5-a]-pyrimidine-6-carboxylic acid (CAS 924846-75-3)
- 3-(3,4,5-Trimethoxyphenyl)acrylaldehyde (CAS 71277-13-9)
- 4-[(2-Bromoacetyl)amino]-N-propylbenzamide (CAS 1138442-94-0)
- Benzyl ((1r,3s)-3-hydroxycyclopentyl)carbamate (CAS 1932508-80-9)
- Eledoisin Related Peptide (CAS 2990-43-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com