6-Bromo-2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one CAS 337463-88-4
| CAS No. | 337463-88-4 |
| Molecular Formula | C7H5BrN2O2 |
| Molecular Weight | 229.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Bromo-2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one (CAS 337463-88-4), molecular formula C7H5BrN2O2 and molecular weight 229.03 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Bromo-2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one (C7H5BrN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Bromo-2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BrN2O2 |
| Molecular Weight | 229.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 6-Bromo-1H-pyrido[2,3-d][1,3]oxazin-2(4H)-one (CAS 335032-38-7)
- 6-Bromo-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one (CAS 41081-77-0)
- 5-Bromo-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 815618-77-0)
- 6-Bromo-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol (CAS 32449-41-5)
- N-p-tolylformamide (CAS 3085-54-9)
- 2-((2,6-Dichlorobenzyl)thio)-3-propyl-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 860609-25-2)
- 2-Chloro-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)nicotinamide (CAS 920506-35-0)
- (1R)-Quinolin-4-yl((2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol dihydrochloride (CAS 24302-67-8)
- Racemic-(5aR,9aR)-tert-butyl 5-oxooctahydropyrido[4,3-f][1,4]oxazepine-8(2H)-carboxylate (CAS 1445951-28-9)
- Benzyl 2-(tert-butyl)-4-oxopiperidine-1-carboxylate (CAS 1245645-34-4)
- N-(chroman-4-yl)acetamide (CAS 194342-62-6)
- N-(4-Ethyl-1H-pyrazol-3-yl)butyramide (CAS 203061-98-7)
- 6-Chloro-5-methyl-7-nitro-1,3-benzoxazol-2-amine (CAS 1820735-45-2)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
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