6-amino-7-chloro-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one CAS 337463-98-6
| CAS No. | 337463-98-6 |
| Molecular Formula | C7H6ClN3O2 |
| Molecular Weight | 199.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-amino-7-chloro-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one.
6-amino-7-chloro-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one (CAS 337463-98-6) is a high-purity analytical reference standard with the molecular formula C7H6ClN3O2 and a molecular weight of 199.59 g/mol.
The molecular framework of 6-amino-7-chloro-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one (C7H6ClN3O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-amino-7-chloro-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6ClN3O2 |
| Molecular Weight | 199.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related amino Standards
- Methyl 3-amino-5-chloro-4-cyano-1H-pyrrole-2-carboxylate (CAS 1243403-89-5)
- Ethyl 3-amino-4-chloro-4,4-difluorobut-2-enoate (CAS 136757-13-6)
- 2-Amino-5-(chloromethyl)-3h,7h-[1,2,4]triazolo[1,5-a]pyrimidin-7-one (CAS 885867-96-9)
- (S)-3-amino-2-(4-chlorophenyl)propanoic acid (CAS 1001227-79-7)
- (4-Amino-3-chloro-phenyl)-acetic acid methyl ester (CAS 101349-30-8)
- Methyl 3-amino-5-chloro-4-methylbenzoate (CAS 1092307-46-4)
- 1-(2-Amino-4-chloro-5-methoxyphenyl)ethanone (CAS 1108658-79-2)
- Methyl 5-Amino-2-chloro-4-methylbenzoate (CAS 1143026-47-4)
Recommended Standards
- 5-Chloro-6-nitro-1,3-dihydroisobenzofuran (CAS 2304496-02-2)
- 6-Chloro-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 69337-31-1)
- 5-Chloro-4-methyl-1H-pyrimido[4,5-d][1,3]oxazin-2(4H)-one (CAS 2459489-14-4)
- 6-Chloro-4-methoxyfuro[3,2-c]pyridin-3(2H)-one (CAS 2762234-14-8)
- 4-Methyl-2-oxabicyclo[2.2.2]octan-3-one (CAS 61405-06-9)
- Phenylbutazone EP Impurity C (CAS 122-66-7)
- 5,5-Dimethyl-2-[1-(4-methylbenzenesulfonyl)piperidine-4-carbonyl]cyclohexane-1,3-dione (CAS 478047-61-9)
- 3,5-Bis(aminomethyl)phenol (CAS 1243394-03-7)
- Diethylstilbestrol Monomethyl Ether (CAS 18839-90-2)
- N,N-Dinitroso Valsartan Desvaleryl Impurity 86 (CAS CATO-C4X-105786)
- 1-(4-Chlorophenyl)-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (CAS 326618-92-2)
- Tetraethylphosphonium Tetrafluoroborate (CAS 665-49-6)
- Atracurium EP Impurity A (CAS 87046-74-0)
- Ac-(5-31)Semaglutide (CAS CATO-C4X-2226279)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com