2-(4-Methoxyphenyl)-N-(2-methylnaphthalen-1-yl)quinoline-4-carboxamide CAS 337504-09-3
| CAS No. | 337504-09-3 |
| Molecular Formula | C28H22N2O2 |
| Molecular Weight | 418.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-Methoxyphenyl)-N-(2-methylnaphthalen-1-yl)quinoline-4-carboxamide (C28H22N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-(4-Methoxyphenyl)-N-(2-methylnaphthalen-1-yl)quinoline-4-carboxamide (CAS 337504-09-3), molecular formula C28H22N2O2 and molecular weight 418.49 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Methoxyphenyl)-N-(2-methylnaphthalen-1-yl)quinoline-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H22N2O2 |
| Molecular Weight | 418.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Methoxyphenyl Standards
- 4-(1-(4-Methoxyphenyl)-4,5-diphenyl-1H-imidazol-2-yl)phenol (CAS 497061-20-8)
- 7-(4-Methoxyphenyl)-2-(4-phenylpiperazin-1-yl)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 1243021-30-8)
- Ethyl 3-{[(4-methoxyphenyl)carbamoyl]methoxy}pyrido[1,2-a]indole-10-carboxylate (CAS 478081-16-2)
- N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide (CAS 192384-87-5)
- 10-[4-(2-methoxyphenyl)piperazine-1-carbonyl]-10h-phenothiazine (CAS 371782-03-5)
- N-(4-methoxyphenyl)-2-(2-((p-tolylthio)methyl)-1H-benzo[d]imidazol-1-yl)acetamide (CAS 339100-11-7)
- 3-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-1H-pyrimido[5,4-b]indole-2,4(3H,5H)-dione (CAS 133399-65-2)
- 1-[1-(4-Methoxyphenyl)cyclopropanecarbonyl]-4-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]piperidine (CAS 1775460-17-7)
Recommended Standards
- 2-((5-Benzyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-fluorophenyl)acetamide (CAS 332907-34-3)
- 2-Butyl-6-(9H-carbazol-9-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS 2623274-48-4)
- 2-((4-Ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-sulfamoylphenyl)acetamide (CAS 578755-91-6)
- 3-((2-Trityl-2H-tetrazol-5-yl)methyl)phenol (CAS 885278-40-0)
- Cyclopentyl(4-methoxyphenyl)methanone (CAS 15831-52-4)
- (2E)-3-(2,4-Dichlorophenyl)-1-phenylprop-2-en-1-one (CAS 22966-15-0)
- (5-Bromofuran-2-yl)(6,7-dihydrothieno[3,2-c]pyridin-5(4h)-yl)methanone (CAS 1280805-09-5)
- 4-(5-Bromofuran-2-yl)but-3-en-2-one (CAS 451479-12-2)
- N1-(cyclopentylmethyl)-N1-methylethane-1,2-diamine (CAS 933702-50-2)
- N-(2,5-Dimethoxyphenyl)-2-(4-fluorophenoxy)propanamide (CAS 617695-97-3)
- Sitagliptin Impurity 14 (CAS 1151240-91-3)
- 2-(Aminomethyl)-5-(difluoromethyl)-3-methylpyridine-6-methanol (CAS 1805438-13-4)
- 6,8-Dibromo-2-phenylquinoline-4-carboxylic acid (CAS 303793-47-7)
- C-telopeptide (CAS 162929-64-8)
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