Amifostine Impurity 8 CAS 33759-44-3

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.33759-44-3
Molecular FormulaC5H10N2O
Molecular Weight114.15 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Amifostine Impurity 8 CAS 33759-44-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Amifostine Impurity 8.

CATO supplies Amifostine Impurity 8 (CAS 33759-44-3), a pharmacopoeial impurity reference standard (molecular formula C5H10N2O, MW 114.15 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Amifostine Impurity 8 (C5H10N2O) contains an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 114.15 g/mol, it falls into the low-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Amifostine Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H10N2O
Molecular Weight114.15 g/mol
Purity>90%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1966
Nitrogen Atoms2

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