1,1-Bis(4-chlorophenyl)-2-(4-methoxybenzenesulfonyl)ethan-1-ol CAS 337919-97-8
| CAS No. | 337919-97-8 |
| Molecular Formula | C21H18Cl2O4S |
| Molecular Weight | 437.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1,1-Bis(4-chlorophenyl)-2-(4-methoxybenzenesulfonyl)ethan-1-ol (C21H18Cl2O4S) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1,1-Bis(4-chlorophenyl)-2-(4-methoxybenzenesulfonyl)ethan-1-ol (CAS 337919-97-8), molecular formula C21H18Cl2O4S and molecular weight 437.34 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H18Cl2O4S |
| Molecular Weight | 437.34 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Bis Standards
- 2-(4-Chlorophenyl)-3-((4-(3-chlorophenyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridine (CAS 861212-34-2)
- 4-Chlorophenyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrole-2-sulfonate (CAS 338397-96-9)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-7-(p-tolyl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1226429-62-4)
- 2-[4-(2-Chlorophenyl)piperazin-1-yl]-7-(4-methylphenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1226450-27-6)
- 2-[4-(3-Chlorophenyl)piperazin-1-yl]-7-(3-methylphenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1242883-94-8)
- 7-(4-Chlorophenyl)-2-(4-(m-tolyl)piperazin-1-yl)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 1242964-70-0)
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- 2-(4-(2-Chlorophenyl)piperazin-1-yl)-7-(o-tolyl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1243025-61-7)
Recommended Standards
- 3-[4-[2-(2,5-Dichloro-4-nitrophenyl)ethyl]-1-piperazinyl]-1,2-benzisothiazole (CAS 160384-38-3)
- Pentafluorophenyl 2-(morpholin-4-ylsulphonyl)benzoate (CAS 950603-27-7)
- ((2R,3S,4R,5R)-5-(6-(Benzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 13484-66-7)
- 2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine-d2[Aprepitant-M2-d2] (CAS 1217645-68-5)
- 1-(2,3,4,5-Tetrahydro-1,4-benzoxazepin-7-yl)ethanol (CAS 1314913-84-2)
- 2-Phenyl-2H-benzo[d][1,2,3]triazole (CAS 1916-72-9)
- 2-((1H-Pyrrol-1-yl)sulfonyl)aniline (CAS 54254-41-0)
- 1-Benzyl3-ethyl(3s,4r)-4-((tert-Butoxycarbonyl)amino)pyrrolidine-1,3-dicarboxylate (CAS 1311254-40-6)
- 2-((2-Fluorophenyl)ethynyl)-4-hydroxy-5-phenyl-6H-1,3-oxazin-6-one (CAS 1956377-05-1)
- 2-(Difluoromethyl)-3,6-dimethoxypyridine-4-sulfonyl chloride (CAS 1805162-25-7)
- (R)-2-(2-Aminoacetamido)propanoic acid (CAS 691-81-6)
- 2-(1-(((4-Acetamidophenyl)sulfonamido)methyl)cyclohexyl)acetic acid (CAS 1175804-00-8)
- tert-butyl (3S,4S)-3-azido-4-fluoro-pyrrolidine-1-carboxylate (CAS 913743-06-3)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
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