6-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2-(4-chlorophenyl)pyrrolo[3,4-e][1,3]thiazine-5,7(6H,7aH)-dione CAS 337920-05-5
| CAS No. | 337920-05-5 |
| Molecular Formula | C20H13Cl2F3N4O2S |
| Molecular Weight | 501.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2-(4-chlorophenyl)pyrrolo[3,4-e][1,3]thiazine-5,7(6H,7aH)-dione is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2-(4-chlorophenyl)pyrrolo[3,4-e][1,3]thiazine-5,7(6H,7aH)-dione (CAS 337920-05-5) is a high-purity analytical reference standard with the molecular formula C20H13Cl2F3N4O2S and a molecular weight of 501.31 g/mol.
6-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2-(4-chlorophenyl)pyrrolo[3,4-e][1,3]thiazine-5,7(6H,7aH)-dione (C20H13Cl2F3N4O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H13Cl2F3N4O2S |
| Molecular Weight | 501.31 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 7-Chloro-2-(3-(9-(pyridin-4-yl)-3,9-diazaspiro[5.5]undecane-3-carbonyl)phenyl)isoindolin-1-one (CAS 913064-47-8)
- 8-Chloro-2-phenyl-3-((1S)-1-((9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)amino)ethyl)isoquinolin-1(2H)-one (CAS 1350643-73-0)
- 2-((5-((9-Chloro-6H-indolo[2,3-b]quinoxalin-6-yl)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 116989-80-1)
- N-(4-Chloro-3-nitrophenyl)-2-((3-cyano-4,6-diphenylpyridin-2-yl)thio)acetamide (CAS 332160-37-9)
- (2Z)-3-[(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}phenyl)amino]-1-(4-methylphenyl)prop-2-en-1-one (CAS 478262-29-2)
- Ethyl 4-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}benzenesulfonamido)benzoate (CAS 338775-49-8)
- Ethyl 10-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-9,11-dioxo-3-oxa-4,10-diazatetracyclo[5.5.1.0^{2,6}.0^{8,12}]tridec-4-ene-5-carboxylate (CAS 321998-78-1)
- 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-{[(4-nitrophenyl)carbamoyl]amino}-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 338399-54-5)
Recommended Standards
- (E)-3-nitro-4-((3-(trifluoromethyl)phenyl)thio)benzaldehyde O-(2,6-dichlorobenzyl) oxime (CAS 477852-21-4)
- N-(2,4-dichloro-5-(2-methoxyethoxy)phenyl)-3-(2-fluoro-4-nitrophenoxy)thiophene-2-carboxamide (CAS 339015-61-1)
- (E)-[(3,4-Dichlorophenyl)methoxy][(3-nitro-4-{[3-(trifluoromethyl)phenyl]sulfanyl}phenyl)methylidene]amine (CAS 477852-20-3)
- N-(2-Bromo-4-nitrophenyl)-2-((5-(3-hydroxynaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide (CAS 332377-21-6)
- 2-(3,4-Dihydroisoquinolin-2(1H)-yl)acetic acid hydrochloride (CAS 200064-94-4)
- 5-Bromo-2H-chromene-3-carboxylic acid (CAS 885270-71-3)
- (R)-(3-Phenyl-4,5-dihydroisoxazol-5-yl)methanol (CAS 119897-89-1)
- (1S,2R,3S,4R)-3-((tert-Butoxycarbonyl)amino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (CAS 1242184-46-8)
- Methyl 2-amino-5-(pyrimidin-2-yloxy)benzoate (CAS 185154-82-9)
- N'-(2-Fluorophenyl)acetohydrazide (CAS 1552322-40-3)
- 6-Isopropoxynicotinaldehyde (CAS 884495-35-6)
- 3-(6-Chloro-3-indolyl)-1-propanamine (CAS 1000525-46-1)
- 5-Iodobenzo[b]thiophene (CAS 20532-38-1)
- Gastric Inhibitory Polypeptide (human) (CAS 100040-31-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com