(2Z)-7-(4-Chlorophenoxy)-2-[(2,5-difluorophenyl)methylidene]-3-phenyl-2,3-dihydro-1H-inden-1-one CAS 337921-33-2
| CAS No. | 337921-33-2 |
| Molecular Formula | C28H17ClF2O2 |
| Molecular Weight | 458.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(2Z)-7-(4-Chlorophenoxy)-2-[(2,5-difluorophenyl)methylidene]-3-phenyl-2,3-dihydro-1H-inden-1-one (CAS 337921-33-2) is a high-purity analytical reference standard with the molecular formula C28H17ClF2O2 and a molecular weight of 458.88 g/mol.
(2Z)-7-(4-Chlorophenoxy)-2-[(2,5-difluorophenyl)methylidene]-3-phenyl-2,3-dihydro-1H-inden-1-one (C28H17ClF2O2) contains a steroid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures (2Z)-7-(4-Chlorophenoxy)-2-[(2,5-difluorophenyl)methylidene]-3-phenyl-2,3-dihydro-1H-inden-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H17ClF2O2 |
| Molecular Weight | 458.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
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