(2Z)-2-[(3,4-Dimethoxyphenyl)methylidene]-3-phenyl-7-[3-(trifluoromethyl)phenoxy]-2,3-dihydro-1H-inden-1-one CAS 337921-81-0
| CAS No. | 337921-81-0 |
| Molecular Formula | C31H23F3O4 |
| Molecular Weight | 516.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies (2Z)-2-[(3,4-Dimethoxyphenyl)methylidene]-3-phenyl-7-[3-(trifluoromethyl)phenoxy]-2,3-dihydro-1H-inden-1-one (CAS 337921-81-0), a certified reference material (molecular formula C31H23F3O4, MW 516.51 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, (2Z)-2-[(3,4-Dimethoxyphenyl)methylidene]-3-phenyl-7-[3-(trifluoromethyl)phenoxy]-2,3-dihydro-1H-inden-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 516.51 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H23F3O4 |
| Molecular Weight | 516.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Z Standards
- Ethyl 7-(3,4-dimethoxyphenyl)-2-methyl-5-oxo-4-(4-(trifluoromethyl)phenyl)-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 333308-93-3)
- 1-Benzyl-3-[(2,4-dimethoxyphenyl)methyl]-3-(4-iodophenyl)thiourea (CAS 306730-51-8)
- 3-(3,4-Dimethoxyphenyl)-2,3,4,5,10,11-hexahydro-11-(3-phenoxyphenyl)-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 297157-92-7)
- 2-((1-(2,4-Dimethoxyphenyl)-2-(tritylthio)ethyl)amino)acetic acid (CAS 823829-31-8)
- Butyl 7-(3,4-dimethoxyphenyl)-2-methyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 332928-79-7)
- 4-(3,4-Dimethoxyphenyl)-2-(((5-phenyl-1,3,4-oxadiazol-2-yl)methyl)thio)-6-(p-tolyl)nicotinonitrile (CAS 337497-81-1)
- 2-((2-(2,5-Dimethoxyphenyl)-2-oxoethyl)thio)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 477331-64-9)
- 2-((2-(3,4-Dimethoxyphenyl)-2-oxoethyl)thio)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 477331-58-1)
Recommended Standards
- N-Nitroso Pemigatinib (CAS CATO-C4X-30242)
- Lenalidomide Impurity 42 (CAS CATO-C4X-190342)
- Fluorescein impurity 14 (CAS CATO-C4X-290014)
- TC-N 1752 (CAS 1211866-85-1)
- Deoxysappanone B (CAS 113122-54-6)
- 2-(Chloromethyl)naphtho[1,2-b]thiophene 1,1-dioxide (CAS 931114-48-6)
- 3-(4-Chlorophenyl)-4-oxo-N-(4-(trifluoromethoxy)phenyl)-3,4-dihydrophthalazine-1-carboxamide (CAS 320417-62-7)
- 1-(Cyclobutylmethyl)piperazine (CAS 82534-54-1)
- (E)-3-(2-methyl-4-(trifluoromethoxy)phenyl)acrylic acid (CAS 1588508-08-0)
- 1-(2-Ethoxy-5-methylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1443349-32-3)
- 1-Bromo-3-fluoro-5-(4-methylbenzyl)benzene (CAS 2586127-50-4)
- (3-Methylpyridin-2-yl)(m-tolyl)methanone (CAS 1187165-28-1)
- Bis[bis(3,5-dimethylphenyl)phosphino]methane (CAS 167109-95-7)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com