(2Z)-2,3-Dichloro-N-(6-methoxypyridin-3-yl)-3-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)prop-2-enamide CAS 337922-07-3
| CAS No. | 337922-07-3 |
| Molecular Formula | C17H13Cl2F3N2O2S |
| Molecular Weight | 437.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2Z)-2,3-Dichloro-N-(6-methoxypyridin-3-yl)-3-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)prop-2-enamide.
CATO supplies (2Z)-2,3-Dichloro-N-(6-methoxypyridin-3-yl)-3-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)prop-2-enamide (CAS 337922-07-3), a certified reference material (molecular formula C17H13Cl2F3N2O2S, MW 437.26 g/mol) for analytical method development and quality control.
(2Z)-2,3-Dichloro-N-(6-methoxypyridin-3-yl)-3-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)prop-2-enamide (C17H13Cl2F3N2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H13Cl2F3N2O2S |
| Molecular Weight | 437.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Z Standards
- 1,11-Dichloro-5,7-dioxo-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-6(7H)-carboxamide (CAS 183747-17-3)
- 3-[4-[2-(2,5-Dichloro-4-nitrophenyl)ethyl]-1-piperazinyl]-1,2-benzisothiazole (CAS 160384-38-3)
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- 3,5-Dichloro-2-(tributylstannyl)pyrazine (CAS 446285-70-7)
- 2,3-Dichloro-α-(2,3-dichloro-4-methoxyphenyl)-4-methoxy-benzeneacetic Acid Ethyl Ester (CAS 316382-53-3)
- 3,4-Dichloro-N-(2-methyl-2-((3-(trifluoromethyl)benzyl)thio)propyl)benzamide (CAS 339104-44-8)
Recommended Standards
- Phenyl(2-(tributylstannyl)cyclopropyl)methanol (CAS 832132-88-4)
- 2-(4-Bromophenyl)-N'-[(1E)-(4-fluorophenyl)methylidene]imidazo[1,2-a]pyridine-6-carbohydrazide (CAS 866138-01-4)
- 3-(2,6-Dichlorophenyl)-N-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-5-methylisoxazole-4-carboxamide (CAS 685830-87-9)
- 3-((4-Bromophenyl)thio)-1-(2-methoxy-5-nitrophenyl)pyrrolidine-2,5-dione (CAS 882749-48-6)
- Diethyl Decarboxylated Compound (CAS 177838-59-4)
- H-D-Arg(NO2)-OH (CAS 66036-77-9)
- 2-[(3,4-Dichlorophenyl)methoxy]-5-[(4-methoxyphenoxy)methyl]-1,3-thiazole (CAS 339105-02-1)
- (3,5-Dimethylphenyl)(4-methylpyridin-3-yl)methanone (CAS 1187167-90-3)
- 5-(4-(Trifluoromethoxy)phenyl)-1-indanone (CAS 1261586-76-8)
- 4-Methoxyphenyl 3-O-Benzyl-4,6-O-benzylidene-β-D-glucopyranoside (CAS 303127-81-3)
- Boc-Phe-Leu-OMe (CAS 64152-76-7)
- 3,6-Dibromo-5-(difluoromethyl)picolinic acid (CAS 1805049-17-5)
- 3-(3,4-Dihydro-2h-1,5-benzodioxepin-7-yl)propanoic acid (CAS 1018131-87-7)
- Semaglutide Impurity 133 (CAS CATO-C4X-2226133)
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