N-(4-Methoxyphenyl)-2-{N-[3-(trifluoromethyl)phenyl]4-chlorobenzenesulfonamido}acetamide CAS 337922-19-7
| CAS No. | 337922-19-7 |
| Molecular Formula | C22H18ClF3N2O4S |
| Molecular Weight | 498.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-(4-Methoxyphenyl)-2-{N-[3-(trifluoromethyl)phenyl]4-chlorobenzenesulfonamido}acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N-(4-Methoxyphenyl)-2-{N-[3-(trifluoromethyl)phenyl]4-chlorobenzenesulfonamido}acetamide (CAS 337922-19-7), molecular formula C22H18ClF3N2O4S and molecular weight 498.90 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(4-Methoxyphenyl)-2-{N-[3-(trifluoromethyl)phenyl]4-chlorobenzenesulfonamido}acetamide (C22H18ClF3N2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H18ClF3N2O4S |
| Molecular Weight | 498.90 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- (6-Bromo-3-fluoroimidazo[1,2-a]pyridin-2-yl)methanol (CAS 2306265-18-7)
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- Semaglutide238 (CAS CATO-C4X-2226238)
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