2-[[(4-chlorophenyl)sulfonyl]-3-(trifluoromethyl)anilino]-N-phenylacetamide CAS 337922-22-2
| CAS No. | 337922-22-2 |
| Molecular Formula | C21H16ClF3N2O3S |
| Molecular Weight | 468.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-[[(4-chlorophenyl)sulfonyl]-3-(trifluoromethyl)anilino]-N-phenylacetamide (CAS 337922-22-2), molecular formula C21H16ClF3N2O3S and molecular weight 468.88 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-[[(4-chlorophenyl)sulfonyl]-3-(trifluoromethyl)anilino]-N-phenylacetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 468.88 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-[[(4-chlorophenyl)sulfonyl]-3-(trifluoromethyl)anilino]-N-phenylacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H16ClF3N2O3S |
| Molecular Weight | 468.88 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related chlorophenyl Standards
- (3E)-1-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-3-({2-[3-(trifluoromethyl)phenoxy]ethoxy}imino)propan-1-one (CAS 339279-44-6)
- 4-(4-Chlorophenyl)-2-(4-fluorophenoxy)-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 303984-59-0)
- (E)-({6-[(4-chlorophenyl)sulfanyl]imidazo[2,1-b][1,3]thiazol-5-yl}methylidene)[(2,6-dichlorophenyl)methoxy]amine (CAS 339022-82-1)
- (E)-6-((4-chlorophenyl)thio)imidazo[2,1-b]thiazole-5-carbaldehyde O-(2,4-dichlorobenzyl) oxime (CAS 339022-78-5)
- Ethyl 5-(2-chlorophenyl)-2-(2-methoxybenzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 324566-08-7)
- 3-((4-Chlorophenyl)sulfonyl)-1-cyclopentyl-2-imino-10-methyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606955-69-5)
- 3-((4-Chlorophenyl)sulfonyl)-1-cyclopentyl-2-imino-8-methyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606956-05-2)
- N-(2-(4-(1-((4-chlorophenyl)sulfonyl)-1H-pyrazol-3-yl)phenoxy)ethyl)-N-methylpyridin-2-amine (CAS 477713-83-0)
Recommended Standards
- 2-((4-Chloro-N-phenylphenyl)sulfonamido)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 339102-58-8)
- Ertugliflozin Impurity 36 (CAS CATO-C4X-301136)
- Cyclohexyl 4-(5-(2-chloro-4-nitrophenyl)furan-2-carboxamido)benzoate (CAS 7061-86-1)
- 3-{[(4-bromophenyl)methyl]sulfanyl}-5-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-4-ethyl-4H-1,2,4-triazole (CAS 344268-63-9)
- 2-(pyridin-4-ylmethoxy)propanoic acid hydrochloride (CAS 1864058-32-1)
- Carbon supported palladium hydroxide (CAS 12135-22-7)
- 1,5-(DI-BOC)-3-HYDROXY-1,5-DIAZOCANE (CAS 862703-09-1)
- 5-((2,3,5,6-Tetrafluorophenoxy)methyl)furan-2-carboxylic acid (CAS 406470-51-7)
- 3,5-Dicyclopropyl-1H-pyrazole (CAS 1288339-30-9)
- 5-(3-Methylthiophen-2-yl)thiophene-2-carboxylic acid (CAS 1342606-57-8)
- Dichloroacetaldehyde Hydrate Solution (Second Source), 1,000 mg/L, 1 ml (CAS 79-02-7)
- 3-Fluoro-2-iodothiophene (CAS 32431-80-4)
- rel-(1R,2S)-2-(Fluoromethyl)cyclopropane-1-carboxylic acid (CAS 2489502-73-8)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
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