(2Z)-2,3-Dichloro-3-[(4-chlorophenyl)methanesulfonyl]-N-(6-methoxypyridin-3-yl)prop-2-enamide CAS 337922-36-8
| CAS No. | 337922-36-8 |
| Molecular Formula | C16H13Cl3N2O4S |
| Molecular Weight | 435.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2Z)-2,3-Dichloro-3-[(4-chlorophenyl)methanesulfonyl]-N-(6-methoxypyridin-3-yl)prop-2-enamide is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (2Z)-2,3-Dichloro-3-[(4-chlorophenyl)methanesulfonyl]-N-(6-methoxypyridin-3-yl)prop-2-enamide (CAS 337922-36-8), a certified reference material (molecular formula C16H13Cl3N2O4S, MW 435.71 g/mol) for analytical method development and quality control.
The molecular framework of (2Z)-2,3-Dichloro-3-[(4-chlorophenyl)methanesulfonyl]-N-(6-methoxypyridin-3-yl)prop-2-enamide (C16H13Cl3N2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2Z)-2,3-Dichloro-3-[(4-chlorophenyl)methanesulfonyl]-N-(6-methoxypyridin-3-yl)prop-2-enamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13Cl3N2O4S |
| Molecular Weight | 435.71 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Z Standards
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- 6,7-Dichloro-2,4-bis(4-chlorophenyl)phthalazin-1(2H)-one (CAS 672951-09-6)
- 3,3'-((2,5-Dichloro-1,4-phenylene)bis(azanediyl))bis(1H-isoindol-1-one) (CAS 51016-63-8)
- 4-[5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methylbenzoic acid (CAS 1332698-41-5)
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Recommended Standards
- N-Benzyl-N-[1-(4-bromophenyl)-2,5-dioxopyrrolidin-3-yl]-2-chloroacetamide (CAS 1858241-22-1)
- benzyl (S)-2-(1-Bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate (CAS 1420478-87-0)
- 4-Chloro-N-[5-oxo-2,4-bis(trifluoromethyl)-5,6-dihydro-1,6-naphthyridin-6-yl]benzamide (CAS 860785-18-8)
- Cathasterone-d3 (CAS 1380235-47-1)
- 5-Chloro-1-isopropyl-1H-benzo[d]imidazol-2-amine (CAS 1154369-65-9)
- AQ-13 Dihydrochloride (CAS 169815-40-1)
- 1-(4-Chlorophenyl)-2-methoxyethan-1-amine (CAS 391233-75-3)
- n-(5-Methyl-1,2-oxazol-3-yl)-2-(piperazin-1-yl)acetamide (CAS 923256-54-6)
- 3-Mercapto-2-methylpentanal (CAS 227456-28-2)
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