2-[N-(4-Chlorophenyl)benzenesulfonamido]-N,N-dimethylacetamide CAS 337922-41-5
| CAS No. | 337922-41-5 |
| Molecular Formula | C16H17ClN2O3S |
| Molecular Weight | 352.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-[N-(4-Chlorophenyl)benzenesulfonamido]-N,N-dimethylacetamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-[N-(4-Chlorophenyl)benzenesulfonamido]-N,N-dimethylacetamide (CAS 337922-41-5), a certified reference material (molecular formula C16H17ClN2O3S, MW 352.84 g/mol) for analytical method development and quality control.
Based on its molecular formula C16H17ClN2O3S, 2-[N-(4-Chlorophenyl)benzenesulfonamido]-N,N-dimethylacetamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 352.84 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H17ClN2O3S |
| Molecular Weight | 352.84 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-((4-Chloro-N-phenylphenyl)sulfonamido)-N,N-dimethylacetamide (CAS 93018-18-9)
- 2-Chloro-1-[4-(2-naphthalenylsulfonyl)-1-piperazinyl]ethanone (CAS 565168-21-0)
- 2-Chloro-N-(4-{[(3-methylphenyl)amino]- sulfonyl}phenyl)propanamide (CAS 1365962-14-6)
- 2-Chloro-5-phenyl-N-(pyridin-2-ylmethyl)thieno[2,3-d]pyrimidin-4-amine (CAS 814918-52-0)
- Ethyl 3-(2-methylpiperidin-1-yl)propanoate (CAS 1094629-90-9)
- 1-(4-Methoxyphenyl)-6,7-dihydro-1H-indazol-4(5H)-one (CAS 945363-51-9)
- 3-(tert-Butyl)-2,5-dihydroxybenzaldehyde (CAS 192803-37-5)
- (3-Fluoro-4-isobutoxyphenyl)methanol (CAS 1039931-95-7)
- N-(2-ethylphenyl)-1,3-benzothiazol-2-amine (CAS 852399-65-6)
- N-(2,4-Difluorobenzyl)-2-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide (CAS 1170077-43-6)
- Azelnidipine Impurity 3 (CAS 170749-59-4)
- 1-(7-Amino-3,4-dihydroisoquinolin-2(1H)-yl)-2-methylpropan-1-one (CAS 1017674-92-8)
- 4-((Tert-butyldimethylsilyl)oxy)-1H-pyrazole (CAS 226989-29-3)
- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
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