6-((Phenylsulfonyl)methyl)-2-(pyridin-4-yl)pyrimidin-4(3H)-one CAS 337923-71-4
| CAS No. | 337923-71-4 |
| Molecular Formula | C16H13N3O3S |
| Molecular Weight | 327.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-((Phenylsulfonyl)methyl)-2-(pyridin-4-yl)pyrimidin-4(3H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 6-((Phenylsulfonyl)methyl)-2-(pyridin-4-yl)pyrimidin-4(3H)-one (CAS 337923-71-4), a certified reference material (molecular formula C16H13N3O3S, MW 327.36 g/mol) for analytical method development and quality control.
The molecular framework of 6-((Phenylsulfonyl)methyl)-2-(pyridin-4-yl)pyrimidin-4(3H)-one (C16H13N3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-((Phenylsulfonyl)methyl)-2-(pyridin-4-yl)pyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13N3O3S |
| Molecular Weight | 327.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Phenylsulfonyl Standards
- 5-(Phenylsulfonyl)-4,5-dihydro-1H-pyrrolo[3,2-c:4,5-c']dipyridin-3(2H)-one (CAS 1956382-25-4)
- (E)-3-(1-(phenylsulfonyl)-1H-indol-5-yl)acrylic acid (CAS 1372762-53-2)
- (2E)-5-[3-[(Phenylsulfonyl)amino]phenyl]-2-penten-4-ynoic Acid 151720-90-0 Dehydroxyamino Oxamflatin Acid (CAS 151720-90-0)
- (1-(Phenylsulfonyl)piperidine-4-carbonyl)glycine (CAS 1017421-58-7)
- 1-(Phenylsulfonyl)spiro[indoline-3,4'-piperidine] (CAS 404869-33-6)
- 1-(phenylsulfonyl)-1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester (CAS 146603-30-7)
- 3-Oxo-3-(1-(phenylsulfonyl)-1H-indol-2-yl)propanenitrile (CAS 1265234-00-1)
- 4-Oxo-4-[4-(phenylsulfonyl)-1-piperazinyl]-2-butenoic acid (CAS 741729-15-7)
Recommended Standards
- 5-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-phenyl-4H-1,2,4-triazole-3-thiol (CAS 609792-84-9)
- Benzyl 2-((4-oxo-4H-pyrido[1,2-a][1,3,5]triazin-2-yl)thio)acetate (CAS 896331-75-2)
- 4-Nitro-N-(3-oxo-3-(pyrrolidin-1-yl)propyl)benzenesulfonamide (CAS 925886-35-7)
- Benzyl 2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetate (CAS 896376-66-2)
- N-methyl-N-(thiophen-3-ylmethyl)piperidine-4-carboxamide hydrochloride (CAS 1258651-66-9)
- 3-Cyano-N-(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide (CAS 1351620-30-8)
- 3-(Thiophen-2-yl)-6-(trifluoromethyl)thieno[3,2-b]pyridine (CAS 478080-15-8)
- Cholesterol ethyl carbonate (CAS 23836-43-3)
- Dehydro Lonafarnib (CAS 817202-00-9)
- Tert-butyl 4-(3-nitrobenzyl)piperazine-1-carboxylate (CAS 203047-33-0)
- 4-Cyano-2-(difluoromethyl)pyridine-3-acetic acid (CAS 1806764-68-0)
- PBDE No.17 (CAS 147217-75-2)
- (E)-N,N’-Diphenylformimidamide (CAS 148651-26-7)
- (Cys2)-Neuropeptide Y-8-aminooctanoyl-(D-Cys27)-Neuropeptide Y (25-32) (H-3298.0500) (CAS 128806-04-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com