Ezetimibe Impurity 123 CAS 3382-62-5
| CAS No. | 3382-62-5 |
| Molecular Formula | C13H10FNO |
| Molecular Weight | 215.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ezetimibe Impurity 123 (C13H10FNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Ezetimibe Impurity 123 (CAS 3382-62-5, C13H10FNO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ezetimibe Impurity 123 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10FNO |
| Molecular Weight | 215.22 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 108 (CAS 2304449-25-8)
- Ezetimibe Impurity 47 (CAS 3382-63-6)
- Ezetimibe Impurity 55 (CAS 1829558-53-3)
- Ezetimibe Impurity 69 (CAS 6744-65-6)
- Ezetimibe Impurity 37 (CAS 149437-76-3)
- Ezetimibe Impurity 73 (CAS 845790-38-7)
- Ezetimibe Impurity 50 (CAS 3369-35-5)
- Ezetimibe Impurity 111 (CAS CATO-C4X-1098111)
Recommended Standards
- Pitavastatin Impurity 82 (CAS 782-01-4)
- (E)-4-(((2-fluorophenyl)imino)methyl)phenol (CAS 1829558-56-6)
- tert-Butyl 3-(1-fluoro-2-oxoethylidene)azetidine-1-carboxylate (CAS 2383712-87-4)
- rel-(2S,7aR)-Ethyl 2-fluoro-5-oxohexahydro-1H-pyrrolizine-7a-carboxylate (CAS 2454498-75-8)
- Mosapride Impurity 23 (CAS CATO-C4X-104423)
- Pioglitazone impurity 56 (CAS 1258625-43-2)
- Bazedoxifene Acetate Impurity 14 (CAS 198479-63-9)
- 4-(Cyclododecylamino)-4-oxobutanoic acid (CAS 392714-62-4)
- 2-(2-Bromo-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanamine (CAS 1443290-24-1)
- 4-Chloro-N-[(5-methylfuran-2-yl)methyl]aniline (CAS 51305-71-6)
- 3-(2-Methyl-1H-imidazol-1-yl)propan-1-ol (CAS 22159-27-9)
- 5-Bromo-3-cyano-2-methylbenzoic acid (CAS 1807209-30-8)
- (4-Amino-2-chlorophenyl)(morpholino)methanone (CAS 926201-77-6)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com