N-((E)-{2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}methylidene)nicotinohydrazide CAS 338393-70-7
| CAS No. | 338393-70-7 |
| Molecular Formula | C17H13ClN4O2S |
| Molecular Weight | 372.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N-((E)-{2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}methylidene)nicotinohydrazide (CAS 338393-70-7), a certified reference material (molecular formula C17H13ClN4O2S, MW 372.83 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, N-((E)-{2-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}methylidene)nicotinohydrazide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 372.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H13ClN4O2S |
| Molecular Weight | 372.83 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Recommended Standards
- Methyl 5-[(4-chlorophenyl)sulfanyl]-4-formyl-1-phenyl-1H-pyrazole-3-carboxylate (CAS 449778-53-4)
- N-((E)-{4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}methylidene)isonicotinohydrazide (CAS 338393-62-7)
- Methyl 4-((4-chlorophenyl)thio)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate (CAS 320419-43-0)
- N-(4-(4-Chlorophenyl)thiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide (CAS 515841-78-8)
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