6-(4-Fluorophenyl)-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine CAS 338394-83-5

Purity 97%+In StockPharmaceutical Standards
CAS No.338394-83-5
Molecular FormulaC12H10FN5S
Molecular Weight275.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(4-Fluorophenyl)-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine CAS 338394-83-5 chemical structure

Description

CATO supplies 6-(4-Fluorophenyl)-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 338394-83-5), a certified reference material (molecular formula C12H10FN5S, MW 275.30 g/mol) for analytical method development and quality control.

The molecular framework of 6-(4-Fluorophenyl)-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (C12H10FN5S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H10FN5S
Molecular Weight275.30 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms5
Sulfur Atoms1

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