N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-methylbenzenesulfonamide CAS 338397-27-6
| CAS No. | 338397-27-6 |
| Molecular Formula | C13H10ClF3N2O2S |
| Molecular Weight | 350.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-methylbenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-methylbenzenesulfonamide (CAS 338397-27-6), molecular formula C13H10ClF3N2O2S and molecular weight 350.74 g/mol, is a CATO reference standard with documented purity and traceability.
N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-methylbenzenesulfonamide (C13H10ClF3N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H10ClF3N2O2S |
| Molecular Weight | 350.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
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Recommended Standards
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- 2-(1-Aminoethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide (CAS 1095823-56-5)
- (R)-2-(1-aminoethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide (CAS 1095823-62-3)
- 2-Amino-2-(4-(trifluoromethyl)phenyl)acetamide (CAS 203065-99-0)
- 1-(2-Chloroethyl)-3-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 74025-56-2)
- 2-Butyl-5-methyl-3-phenylfuran (CAS 147328-19-6)
- 2-[(1r,2s)-2-hydroxycyclohexyl]acetonitrile (CAS 74708-24-0)
- 4-[(Dimethylamino)methylidene]-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 339020-90-5)
- Modafinil-d10 Carboxylate (CAS 1246819-82-8)
- 2-(Quinolin-6-yl)ethan-1-amine (CAS 910381-48-5)
- 3,3-Dimethoxypropanamide (CAS 6191-92-0)
- 3,3'-([1,1'-Biphenyl]-4,4'-diylbis(oxy))dianiline (CAS 105112-76-3)
- D-Leu14-Tirzepatide (CAS CATO-CPTD788920)
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