1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(prop-2-yn-1-yl)-1H-pyrrole-2-carboxamide CAS 338397-74-3
| CAS No. | 338397-74-3 |
| Molecular Formula | C14H9ClF3N3O |
| Molecular Weight | 327.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 327.69 g/mol gives 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(prop-2-yn-1-yl)-1H-pyrrole-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(prop-2-yn-1-yl)-1H-pyrrole-2-carboxamide (CAS 338397-74-3), molecular formula C14H9ClF3N3O and molecular weight 327.69 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(prop-2-yn-1-yl)-1H-pyrrole-2-carboxamide (C14H9ClF3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 327.69 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H9ClF3N3O |
| Molecular Weight | 327.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-Chloro-3-(4-methoxyphenyl)-6-(trifluoromethyl)-[1,2,3]triazolo[1,5-a]pyridine (CAS 1400872-35-6)
- 3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trimethylsilyl)pyridin-2(1H)-one (CAS 1417647-20-1)
- 6-Chloro-9-ethyl-8-(6-(trifluoromethyl)pyridin-3-yl)-9H-purine (CAS 1610703-70-2)
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- 3-Chloro-2-(2-methyl-4-(1H-pyrazol-5-yl)-1H-imidazol-1-yl)-5-(trifluoromethyl)pyridine (CAS 303150-53-0)
- 2-((2-((4-Chloro-2-(trifluoromethyl)phenyl)amino)-2-oxoethyl)thio)acetic acid (CAS 338421-31-1)
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Recommended Standards
- 1-((6-Chloropyridin-3-yl)methyl)-6-methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile (CAS 865660-40-8)
- N-(2-benzoyl-4-chlorophenyl)-2,2,2-trifluoroacetamide (CAS 69559-40-6)
- N3-imino[4-(trifluoromethyl)phenyl]methyl-6-chloronicotinamide (CAS 266303-66-6)
- Ethyl N-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]carbamothioyl}carbamate (CAS 1206641-15-7)
- 4-(2-(2,4-Dioxothiazolidin-5-ylidene)acetamido)benzoic acid (CAS 378224-67-0)
- 2-(Phenethylthio)acetonitrile (CAS 17377-30-9)
- (1,3-Dimethyl-5-(4-methyl-1,4-diazepan-1-yl)-1H-pyrazol-4-yl)methanamine (CAS 1152579-20-8)
- N-(4-fluorobenzyl)-1-(1-methyl-1H-pyrazol-5-yl)methanamine hydrochloride (CAS 1856041-06-9)
- Tolvaptan Impurity 125 (CAS CATO-C4X-1955125)
- 2-Chloro-1-(4-((dimethylamino)methyl)piperidin-1-yl)ethanone (CAS 1183213-55-9)
- 2,6-CFAD 2-Chloro-6-fluorobenzaldehyde 2-FLUORO-6-CHLORO BENZALDEHYDE 387-45-1 AKOS BBS-00003159 AS03022 LABOTEST-BB LT00942032 LABOTEST-BB LT03331028 TIMTEC-BB SBB040205 (CAS 387-45-1)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
- 3880-99-7 Benzoic acid-(carboxy-13C) Benzoic acid-|A-13C (CAS 3880-99-7)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
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