5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(1E)-{[(2,4-dichlorophenyl)methoxy]amino}methylidene]-4,5-dihydro-1,2-oxazole-3-carboxamide CAS 338399-37-4
| CAS No. | 338399-37-4 |
| Molecular Formula | C19H15Cl3F3N5O3 |
| Molecular Weight | 524.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(1E)-{[(2,4-dichlorophenyl)methoxy]amino}methylidene]-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 338399-37-4), a certified reference material (molecular formula C19H15Cl3F3N5O3, MW 524.71 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(1E)-{[(2,4-dichlorophenyl)methoxy]amino}methylidene]-4,5-dihydro-1,2-oxazole-3-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 524.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(1E)-{[(2,4-dichlorophenyl)methoxy]amino}methylidene]-4,5-dihydro-1,2-oxazole-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H15Cl3F3N5O3 |
| Molecular Weight | 524.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related chloro Standards
- 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 321432-28-4)
- 3-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-5-({[(2,6-dichlorophenyl)methyl]sulfanyl}methyl)-4-phenyl-4H-1,2,4-triazole (CAS 344271-21-2)
- 2-Chloro-3,4-bis((4-methoxybenzyl)oxy)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide (CAS 1225208-44-5)
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,6-diiodophenol (CAS 923200-10-6)
- 1-(2-(2-Chloro-6H-indolo[2,3-b]quinoxalin-6-yl)acetyl)-4-(1-(4-methoxyphenyl)ethylidene)-3-methyl-1H-pyrazol-5(4H)-one (CAS 119457-20-4)
- 6-Chloro-4-(1-chloro-2-methylpropan-2-yl)pyridazin-3(2H)-one (CAS 117144-78-2)
- 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(3-methyl-5-oxo-1-phenyl-1,2,4-triazolidin-3-yl)-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 351858-44-1)
- 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(1E)-({[3-(trifluoromethyl)phenyl]methoxy}amino)methylidene]-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 321432-34-2)
Recommended Standards
- (3S,6R,7S,8S,12R,13S,15S)-15-amino-12,13-epoxy-4,4,6,8,12,16-hexamethyl-3,7-dihydroxy-17-(2-methyl-4-thiazolyl)-5-oxo-16(+/-)-heptadecenoic acid (CAS 219990-25-7)
- Ixabepilone Impurity 4 (CAS 1220999-09-6)
- 3-((2-(tert-Butyl)-4-(hydroxymethyl)-5-methylphenyl)thio)-6-cyclohexyl-4-hydroxy-6-(4-hydroxyphenethyl)-5,6-dihydro-2H-pyran-2-one (CAS 197915-45-0)
- 1,4:5,8-Dimethanonaphthalene, 6,7-dibromo-1,2,3,4,10,10-hexachloro-1,4,4a,5,6,7,8,8a-octahydro-, trans- (8CI) (CAS 20389-65-5)
- (5s)-9-Fluoro-2,3,4,5-tetrahydro-1-benzoxepin-5-ol (CAS 1568193-23-6)
- 2-(2,4-Dimethylphenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 1353498-25-5)
- 2-Aminoethane-1-sulfonic acid hydrochloride (CAS 73328-73-1)
- Geraniol-D5 (CAS 122058-57-5)
- tert-Butyl 4-chloroindoline-1-carboxylate (CAS 1337533-80-8)
- (R)-2-amino-5-(pyrrolidin-2-yl)benzoic acid (CAS 1213974-69-6)
- (S)-Ethyl 4-amino-2,2-difluorodecanoate hydrochloride (CAS 1363408-59-6)
- Tert-butyl (3-hydroxytetrahydro-2H-pyran-4-yl)carbamate (CAS 1822595-10-7)
- 2-Aminophenol-3,4,5,6-D4 (CAS 121887-11-4)
- Steroidogenesis-Activator Polypeptide (rat) (H-8855.0500) (CAS 108563-23-1)
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