4-{[(E)-2-[3-(2-chloro-6-fluorophenyl)-4-cyano-1,2-oxazol-5-yl]ethenyl]amino}benzoic acid CAS 338403-15-9
| CAS No. | 338403-15-9 |
| Molecular Formula | C19H11ClFN3O3 |
| Molecular Weight | 383.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 383.76 g/mol gives 4-{[(E)-2-[3-(2-chloro-6-fluorophenyl)-4-cyano-1,2-oxazol-5-yl]ethenyl]amino}benzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-{[(E)-2-[3-(2-chloro-6-fluorophenyl)-4-cyano-1,2-oxazol-5-yl]ethenyl]amino}benzoic acid (CAS 338403-15-9), a certified reference material (molecular formula C19H11ClFN3O3, MW 383.76 g/mol) for analytical method development and quality control.
4-{[(E)-2-[3-(2-chloro-6-fluorophenyl)-4-cyano-1,2-oxazol-5-yl]ethenyl]amino}benzoic acid (C19H11ClFN3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-{[(E)-2-[3-(2-chloro-6-fluorophenyl)-4-cyano-1,2-oxazol-5-yl]ethenyl]amino}benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H11ClFN3O3 |
| Molecular Weight | 383.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related E Standards
- N-[2-chloro-5-(trifluoromethyl)phenyl]-2-(3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)acetamide (CAS 1008946-71-1)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-methoxyethyl)-1H-pyrrole-2-sulfonamide (CAS 321433-69-6)
- 2-(3-chloro-2-oxo-2,3-dihydro-1H-indol-4-yl)ethyl 4-(trifluoromethyl)benzoate (CAS 303188-00-3)
- N-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-fluoro-N-methylbenzenesulfonohydrazide (CAS 338748-65-5)
- 4-(4-Chloro-3-nitrobenzoyl)-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-65-4)
- 4-(2-Chloro-5-nitrobenzoyl)-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326811-31-7)
- 7-(1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)ethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 303151-82-8)
- 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(4-fluorophenyl)-1H-pyrrole-2-carboxamide 338956-54-0 KS-000039ED (CAS 338956-54-0)
Recommended Standards
- Voriconazole Impurity 5 (CAS 137234-75-4)
- 2-[2,4-bis(fluoranyl)phenyl]-3-(6-chloranyl-5-fluoranyl-pyrimidin-4-yl)-1-(3-chloranyl-1,2,4-triazol-1-yl)butan-2-ol hydrochloride 3-(6-chloro-5-fluoro-4-pyrimidinyl)-1-(3-chloro-1,2,4-triazol-1-yl)-2-(2,4-difluorophenyl)-2-butanol hydrochloride 848469-29-4 A840960 (CAS 848469-29-4)
- Tris(4-chlorophenyl)phosphine (CAS 1159-54-2)
- Voriconazole Impurity 15 (CAS 137234-76-5)
- 1-(2-Fluorophenyl)-3-(piperazin-1-yl)pyrazin-2(1H)-one (CAS 1710471-75-2)
- Dimethyl 2-Bromoisophthalate (CAS 39622-80-5)
- 3-Methoxy-4-(2-oxo-2-phenylethoxy)benzaldehyde (CAS 723332-14-7)
- (S)-1-(Furan-2-yl)ethan-1-amine (CAS 27948-38-5)
- 5-Nitroso-quinolin-8-ol (CAS 3565-26-2)
- N-(4-(Acridin-9-ylamino)phenyl)benzamide (CAS 76015-18-4)
- (2R)-1-(2,2,2-trifluoroethoxy)propan-2-ol (CAS 1568041-96-2)
- 1-(2,5-Dichlorobenzoyl)pyrrolidine-2-carboxylic acid (CAS 1101837-02-8)
- 3-(4-Fluorophenyl)-3-(methylamino)butanoic acid (CAS 1463521-26-7)
- Peptide 431 (CAS CATO-CPTD788431)
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