2,2,2-Trichloro-1-(4-(2,6-difluorobenzoyl)-1H-pyrrol-2-yl)ethan-1-one CAS 338403-94-4

Purity 97%+In StockPharmaceutical Standards
CAS No.338403-94-4
Molecular FormulaC13H6Cl3F2NO2
Molecular Weight352.55 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2,2-Trichloro-1-(4-(2,6-difluorobenzoyl)-1H-pyrrol-2-yl)ethan-1-one CAS 338403-94-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2,2-Trichloro-1-(4-(2,6-difluorobenzoyl)-1H-pyrrol-2-yl)ethan-1-one.

2,2,2-Trichloro-1-(4-(2,6-difluorobenzoyl)-1H-pyrrol-2-yl)ethan-1-one (CAS 338403-94-4) is a high-purity analytical reference standard with the molecular formula C13H6Cl3F2NO2 and a molecular weight of 352.55 g/mol.

The molecular framework of 2,2,2-Trichloro-1-(4-(2,6-difluorobenzoyl)-1H-pyrrol-2-yl)ethan-1-one (C13H6Cl3F2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 2,2,2-Trichloro-1-(4-(2,6-difluorobenzoyl)-1H-pyrrol-2-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H6Cl3F2NO2
Molecular Weight352.55 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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