(E)-({6-phenylimidazo[2,1-b][1,3]thiazol-5-yl}methylidene)amino 3-(trifluoromethyl)benzoate CAS 338404-79-8
| CAS No. | 338404-79-8 |
| Molecular Formula | C20H12F3N3O2S |
| Molecular Weight | 415.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 415.39 g/mol gives (E)-({6-phenylimidazo[2,1-b][1,3]thiazol-5-yl}methylidene)amino 3-(trifluoromethyl)benzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (E)-({6-phenylimidazo[2,1-b][1,3]thiazol-5-yl}methylidene)amino 3-(trifluoromethyl)benzoate (CAS 338404-79-8), a certified reference material (molecular formula C20H12F3N3O2S, MW 415.39 g/mol) for analytical method development and quality control.
Structurally, (E)-({6-phenylimidazo[2,1-b][1,3]thiazol-5-yl}methylidene)amino 3-(trifluoromethyl)benzoate (C20H12F3N3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 415.39 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-({6-phenylimidazo[2,1-b][1,3]thiazol-5-yl}methylidene)amino 3-(trifluoromethyl)benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H12F3N3O2S |
| Molecular Weight | 415.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related E Standards
- (E)-({6-phenylimidazo[2,1-b][1,3]thiazol-5-yl}methylidene)amino 3,4-dichlorobenzoate (CAS 338404-86-7)
- (E)-6-phenylimidazo[2,1-b]thiazole-5-carbaldehyde O-(2,4-dichlorobenzoyl) oxime (CAS 338404-78-7)
- (E)-6-phenylimidazo[2,1-b]thiazole-5-carbaldehyde O-(2,4-dichlorobenzyl) oxime (CAS 338395-43-0)
- (E)-6-phenylimidazo[2,1-b]thiazole-5-carbaldehyde O-(2,6-dichlorobenzyl) oxime (CAS 337475-27-1)
- (E)-6-phenylimidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime (CAS 400078-51-5)
- (E)-6-phenylimidazo[2,1-b]thiazole-5-carbaldehyde O-(4-chlorobenzoyl) oxime (CAS 338404-80-1)
- 1-{7-methyl-2-phenylimidazo[1,2-a]pyrimidin-5-yl}-4-(pyridin-2-yl)piperazine (CAS 439096-67-0)
- 1-{7-methyl-2-phenylimidazo[1,2-a]pyrimidin-5-yl}-4-phenylpiperazine (CAS 439096-56-7)
Recommended Standards
- (2R,3R,4S,5R,6S)-2-(acetoxymethyl)-6-((2-cyanopropan-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 66432-53-9)
- 1-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 955964-22-4)
- Adefovir Impurity 4 (CAS 142341-04-6)
- 2-[[3-Methoxy-4-[(4-nitrophenyl)methoxy]phenyl]methylene]-1H-indene-1,3(2H)-dione (CAS 431978-82-4)
- 2-(7-Ethyl-1H-indol-3-yl)-4-oxo-4-phenylbutanoic acid (CAS 937605-05-5)
- 3-Methyl-7-(methylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidine (CAS 6312-64-7)
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- 2-Bromo-1-(5-(hydroxymethyl)isoxazol-3-yl)ethanone (CAS 104776-72-9)
- 2-(3,4-Difluorophenyl)acetohydrazide (CAS 797784-35-1)
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- Propargyl-<I>N</I>-hydroxysuccinimide ester (CAS 1174157-65-3)
- [D-Phe22]Semaglutide (CAS CATO-C4X-2226222)
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