1-(3,5-Dichlorophenyl)-5-methyl-N-(2-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide CAS 338408-92-7
| CAS No. | 338408-92-7 |
| Molecular Formula | C17H11Cl2F3N4O |
| Molecular Weight | 415.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(3,5-Dichlorophenyl)-5-methyl-N-(2-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(3,5-Dichlorophenyl)-5-methyl-N-(2-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 338408-92-7), molecular formula C17H11Cl2F3N4O and molecular weight 415.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3,5-Dichlorophenyl)-5-methyl-N-(2-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (C17H11Cl2F3N4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3,5-Dichlorophenyl)-5-methyl-N-(2-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H11Cl2F3N4O |
| Molecular Weight | 415.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Dichlorophenyl Standards
- 1-(2,4-Dichlorophenyl)-5-methyl-N-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 338398-20-2)
- 1-(2,5-Dichlorophenyl)-5-methyl-N-[3-(trifluoromethyl)phenyl]-1H-1,2,4-triazole-3-carboxamide (CAS 338399-11-4)
- 1-(3,5-Dichlorophenyl)-5-methyl-N-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 338408-45-0)
- N-(2,4-dichlorophenyl)-5-methyl-1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 321431-36-1)
- 5-[(2,4-dichlorophenyl)methylidene]-3-[4-(difluoromethoxy)phenyl]-2-sulfanylideneimidazolidin-4-one (CAS 723332-02-3)
- 2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-5-[3-(trifluoromethyl)phenyl]pyrimidine (CAS 339101-89-2)
- Ethyl 2-[({1-[(2,6-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridin-3-yl}carbamoyl)sulfanyl]acetate (CAS 400084-83-5)
- Ethyl 2-[({1-[(3,4-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridin-3-yl}carbamoyl)sulfanyl]acetate (CAS 338755-59-2)
Recommended Standards
- 1-(2-methoxyethyl)-2-(tributylstannyl)-1H-imidazole (CAS 1995074-82-2)
- 3-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}-1-(4-chlorophenyl)urea (CAS 338397-78-7)
- Di-n-pentyldiphenyltin (CAS 23396-45-4)
- (E)-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-yl}methylidene)[(4-chlorophenyl)methoxy]amine (CAS 318248-53-2)
- 3,5-Diiodo-4-hydroxyphenylpropionic Acid (CAS 13811-11-5)
- 4-Nitrophenethyl acetate (CAS 104-30-3)
- 1-Naphthyl β-D-glucopyranoside (CAS 19939-82-3)
- 3-[4-(1,1,2,3,3,3-Hexafluoro-propoxy)-phenyl]-acrylic acid (CAS 565179-47-7)
- Ethyl 3-hydroxy-2-(hydroxymethyl)propanoate (CAS 99116-11-7)
- 5-methyl-4-[(4-methylpiperazin-1-yl)methyl]isoxazole-3-carboxylic acid,HCl (CAS 1431966-48-1)
- 2H-Furo[2,3-e]indole (CAS 145015-50-5)
- 1,4-Bis(trifluoromethyl)-2,6-dichlorobenzene (CAS 1805517-15-0)
- tert-Butyl 2-(6-bromo-5-methyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoate (CAS 1434643-33-0)
- Semaglutide Impurity 150 xTFA (CAS CATO-C4X-2226150)
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