1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile CAS 338409-11-3

Purity 97%+In StockPharmaceutical Standards
CAS No.338409-11-3
Molecular FormulaC13H9ClF3N5O2
Molecular Weight359.69 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile CAS 338409-11-3 chemical structure

Description

1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (C13H9ClF3N5O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 338409-11-3) is a high-purity analytical reference standard with the molecular formula C13H9ClF3N5O2 and a molecular weight of 359.69 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H9ClF3N5O2
Molecular Weight359.69 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms5

Related Chloro Standards

Recommended Standards

Why CATO?