1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-(1,3-dithian-2-yl)-1H-indole CAS 338410-14-3
| CAS No. | 338410-14-3 |
| Molecular Formula | C18H14ClF3N2S2 |
| Molecular Weight | 414.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-(1,3-dithian-2-yl)-1H-indole (C18H14ClF3N2S2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 414.90 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-(1,3-dithian-2-yl)-1H-indole (CAS 338410-14-3), a certified reference material (molecular formula C18H14ClF3N2S2, MW 414.90 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-(1,3-dithian-2-yl)-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14ClF3N2S2 |
| Molecular Weight | 414.90 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Chloro Standards
- 4-Chloro-2-(((3-(trifluoromethyl)phenyl)thio)methyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine (CAS 885460-28-6)
- 4-Chloro-6-{4-[5-(2,5-dimethoxyphenyl)-1H-pyrazol-3-yl]piperidin-1-yl}pyrimidin-2-amine (CAS 1026092-90-9)
- 2-[[5-Chloro-2-[(1-isopropyl-3-methyl-5-pyrazolyl)amino]-4-pyridyl]amino]-N-methoxybenzamide (CAS 1224887-10-8)
- N-(4-chloro-3-nitrophenyl)-2-(4-cinnamylpiperazin-1-yl)acetamide (CAS 329080-37-7)
- 1-(3-Chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-N-(thiophen-2-ylmethyl)piperidine-4-carboxamide (CAS 444151-92-2)
- 2-Chloro-N-(3-methyl-1-oxo-1-((4-(pyridin-2-yl)thiazol-2-yl)amino)butan-2-yl)benzamide (CAS 956958-66-0)
- Chloro(cinnamyl)triphenyl-l5-phosphane (CAS 69052-20-6)
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Recommended Standards
- 2-(4-((4-Chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)ethanol (CAS 1426290-03-0)
- (4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)(3-chlorobenzo[b]thiophen-2-yl)methanone (CAS 324774-65-4)
- Boc-D-Lys(2-chloro-Z)-OH (CAS 57096-11-4)
- 4-((Anthracen-9-ylmethylene)amino)-3-(2-chlorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478253-90-6)
- 8-(Benzo[b]thiophen-2-yl)-2-morpholino-4H-chromen-4-one (CAS 503468-90-4)
- 1-(4-Nitrobenzyl)-1H-benzo[d]imidazol-2(3H)-one (CAS 913267-50-2)
- 3-[(2-Propoxyethoxy)methyl]pyrrolidinehydrochloride (CAS 1220018-79-0)
- 2-[1-(Piperidin-1-yl)ethyl]-3,4-dihydroquinazolin-4-one (CAS 866009-94-1)
- 3-(Dibenzylamino)-2,2-difluoropropanoic acid (CAS 890146-60-8)
- 3,6-Dihydroxy-1,7-dimethoxy-9H-xanthen-9-one (CAS 262292-34-2)
- 2-(4-Bromophenyl)-5,6,7,8-tetrahydroquinazolin-4(1H)-one (CAS 87753-18-2)
- 4-Amino-3-(4-chlorophenyl)-3-methylbutanoic acid (CAS 1466524-43-5)
- IAdCuCl (CAS 875654-50-5)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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