3-(5,6-Dichloro-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzodiazol-2-yl)-1,2-dihydropyridin-2-one CAS 338412-16-1
| CAS No. | 338412-16-1 |
| Molecular Formula | C20H12Cl2F3N3O |
| Molecular Weight | 438.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(5,6-Dichloro-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzodiazol-2-yl)-1,2-dihydropyridin-2-one (CAS 338412-16-1) is a high-purity analytical reference standard with the molecular formula C20H12Cl2F3N3O and a molecular weight of 438.23 g/mol.
The molecular framework of 3-(5,6-Dichloro-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzodiazol-2-yl)-1,2-dihydropyridin-2-one (C20H12Cl2F3N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-(5,6-Dichloro-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzodiazol-2-yl)-1,2-dihydropyridin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H12Cl2F3N3O |
| Molecular Weight | 438.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloro Standards
- 5-(5,6-Dichloro-1-{[3-(trifluoromethyl)phenyl]methyl}-1H-1,3-benzodiazol-2-yl)-1,2-dihydropyridin-2-one (CAS 338774-01-9)
- Ethyl 2-{2,4-dichloro-5-[5-(4-nitrophenyl)-1H-1,2,3,4-tetrazol-1-yl]phenoxy}acetate (CAS 338961-66-3)
- 3,5-Dichloro-N-{4-[(4-fluorobenzenesulfonyl)methyl]phenyl}benzamide (CAS 338398-78-0)
- 2,3-Dichloro-α-(2,3-dichloro-4-methoxyphenyl)-4-methoxy-benzeneacetic Acid Ethyl Ester (CAS 316382-53-3)
- 3,5-Dichloro-2-(tributylstannyl)pyrazine (CAS 446285-70-7)
- 2-(2,3-Dichloro-4-(4-chloro-3-sulfamoylbenzoyl)phenoxy)acetic acid (CAS 90207-12-8)
- 2-[N-(2,4-Dichloro-5-methoxyphenyl)4-chlorobenzenesulfonamido]-N-methylacetamide (CAS 338961-59-4)
- 3,6-Dichloro-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-1,2-dihydroquinoxalin-2-one (CAS 303986-14-3)
Recommended Standards
- 2-(2,4-Dichlorophenyl)-1-{[3-(trifluoromethyl)phenyl]methoxy}-1H-imidazo[4,5-b]pyridine (CAS 338978-57-7)
- 1-Amino-2-bromo-4-((3-nitrophenyl)amino)anthracene-9,10-dione (CAS 88653-23-0)
- 8'-Fluoro-7'-iodo-6'-((2-methoxyethoxy)methoxy)-3',4'-dihydro-1'H-spiro[[1,3]dioxolane-2,2'-naphthalene] (CAS 2489407-90-9)
- (E)-1-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3-(4-chlorophenyl)prop-2-en-1-one (CAS 338401-30-2)
- 1-Chloro-5,5,7,7-tetramethyl-2-octene (CAS 141-64-0)
- n-Tert-butyl-2-(2-chloroacetamido)acetamide (CAS 1226095-75-5)
- [3-fluoro-4-(2-methyl-1h-imidazol-1-yl)phenyl]methanamine (CAS 1037163-76-0)
- 5',5'''-Bis(4-formylphenyl)-[1,1':3',1'':4'',1''':3''',1''''-quinquephenyl]-4,4''''-dicarbaldehyde (CAS 2417655-42-4)
- 2-Amino-4-(trifluoromethyl)benzonitrile (CAS 1483-54-1)
- (4-(4-(4-(Dimethylamino)phenyl)buta-1,3-dien-1-yl)phenyl)boronic acid (CAS 406719-95-7)
- 3-Formylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1019111-51-3)
- (2E)-3-[(2,4-Dichlorophenyl)amino]-2-(thiophen-3-yl)prop-2-enenitrile (CAS 477851-23-3)
- 5-Chloro-3-ethyl-1-methyl-1H-pyrazole-4-sulfonyl chloride (CAS 1226707-24-9)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
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