1-Benzyl-N-(3,4-difluorophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide CAS 338412-76-3
| CAS No. | 338412-76-3 |
| Molecular Formula | C18H13F2N3O3 |
| Molecular Weight | 357.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-Benzyl-N-(3,4-difluorophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 338412-76-3) is a high-purity analytical reference standard with the molecular formula C18H13F2N3O3 and a molecular weight of 357.31 g/mol.
The molecular framework of 1-Benzyl-N-(3,4-difluorophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (C18H13F2N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 1-Benzyl-N-(3,4-difluorophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H13F2N3O3 |
| Molecular Weight | 357.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- 1,3-Dioxoisoindolin-2-yl 3,4,5-trimethoxybenzoate (CAS 681845-28-3)
- 2-3-4-6-Tetra-O-acetyl-β-D-galactopyranosyl cyanide (CAS 52443-07-9)
- 1-(3,4-Difluorophenyl)-N-(2-methoxyphenyl)-4-oxo-1,4-dihydropyridazine-3-carboxamide (CAS 478063-32-0)
- 4-Amino-2,3-bis(benzoyloxy)-4-oxobutanoic acid (CAS 98341-66-3)
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- Ethyl 3,4-dibromo-5-(difluoromethoxy)phenylacetate (CAS 1804936-37-5)
- 3'-Chloro-2,6-dimethyl-[1,1'-biphenyl]-4-carbaldehyde (CAS 2271442-90-9)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com