2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethyl thiophene-2-carboxylate CAS 338415-52-4
| CAS No. | 338415-52-4 |
| Molecular Formula | C17H17ClF3N3O2S |
| Molecular Weight | 419.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethyl thiophene-2-carboxylate (C17H17ClF3N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethyl thiophene-2-carboxylate (CAS 338415-52-4) is a high-purity analytical reference standard with the molecular formula C17H17ClF3N3O2S and a molecular weight of 419.85 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethyl thiophene-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H17ClF3N3O2S |
| Molecular Weight | 419.85 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Cligosiban (CAS 900510-03-4)
- 6-Ethoxy-1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS 2102411-33-4)
- 3-Nitro-1H-pyrrolo[3,2-b]pyridin-6-amine (CAS 1190312-12-9)
- 4-[(2S)-2-Methylbutyl]-1,1'-biphenyl (CAS 62614-28-2)
- 3-(3-Fluoro-5-hydroxyphenyl)-6,8-dioxabicyclo[3.2.1]Octan-3-ol (CAS 1313254-77-1)
- 4-(Hydroxyimino)piperidine-1-carboxamide (CAS 923106-27-8)
- 5-Bromo-2-tritylisoindoline (CAS 405150-03-0)
- (1R,2S)-2-(Dibutylamino)-1-phenylpropan-1-ol (CAS 115651-77-9)
- N-((1S,3r)-3-allyl-3-hydroxycyclobutyl)-2-naphthamide (CAS 1313759-97-5)
- 3-(2,3-Dimethylphenyl)-1-(2,5-dimethylphenyl)propan-1-one (CAS 898792-77-3)
- Vancomycin Hexapeptide (CAS 115236-65-2)
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