2-(Pyridin-2-yl)-6-(trifluoromethyl)pyrimidine-4-thiol CAS 338418-16-9
| CAS No. | 338418-16-9 |
| Molecular Formula | C10H6F3N3S |
| Molecular Weight | 257.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(Pyridin-2-yl)-6-(trifluoromethyl)pyrimidine-4-thiol (CAS 338418-16-9) is a high-purity analytical reference standard with the molecular formula C10H6F3N3S and a molecular weight of 257.23 g/mol.
The molecular framework of 2-(Pyridin-2-yl)-6-(trifluoromethyl)pyrimidine-4-thiol (C10H6F3N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 2-(Pyridin-2-yl)-6-(trifluoromethyl)pyrimidine-4-thiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6F3N3S |
| Molecular Weight | 257.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Pyridin Standards
- 2-(Pyridin-3-yl)-6-(trifluoromethyl)pyrimidine-4-thiol (CAS 541550-01-0)
- N-(5-(Pyridin-4-yl)-1,3,4-oxadiazol-2-yl)isoxazole-5-carboxamide (CAS 919753-43-8)
- Ethyl 2-((pyridin-4-ylmethyl)amino)nicotinate (CAS 1035055-46-9)
- N-(1-(Pyridin-2-yl)pyrrolidin-3-yl)furan-2-carboxamide (CAS 1795193-35-9)
- 1-(Pyridin-2-yl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxylic acid (CAS 934405-67-1)
- 1-(Pyridin-3-yl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxylic acid (CAS 2251053-50-4)
- 1-pyridin-2-yl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 98534-86-2)
- Ethyl (2-(pyridin-2-ylamino)phenyl)carbamate (CAS 89659-78-9)
Recommended Standards
- 2-(4-(Trifluoromethyl)phenyl)thiazole-5-carbaldehyde (CAS 447406-52-2)
- 1-Iodooctane-d17 (stabilized with copper) (CAS 340256-37-3)
- 2,3-Difluoro-6-pivalamidobenzoic acid (CAS 874784-13-1)
- (2,6-Difluorobenzoyl)-l-valine (CAS 956684-24-5)
- 4-Amino-N-(1-methylazepan-2-ylidene)benzenesulfonamide (CAS 126826-62-8)
- 5-Methylsulfanyl-3-trifluoromethyl-isothiazole-4-carboxylic acid ethyl ester (CAS 157984-52-6)
- Ethyl 3-(trifluoromethyl)picolinate (CAS 952182-76-2)
- N,3-Bis(3-methoxyphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-50-6)
- N-(3-Chlorophenyl)-5-(quinolin-8-yl)pyridin-3-amine (CAS 875147-06-1)
- 3-Ethyl-4-methoxybenzaldehyde (CAS 103323-26-8)
- Mal-PEG2-CH2COOH (CAS 173323-23-4)
- 3-(5-(3-Chloro-4-methylphenyl)furan-2-yl)-2-cyanoacrylic acid (CAS 853347-78-1)
- 7-bromo-8-fluoro-2-methoxy-3a-methyl-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxalin-4-one (CAS 1803570-46-8)
- Angiotensin III Antipeptide (CAS 133605-55-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com