4-(2,4-Dichlorobenzyl)-N-(4-fluorophenyl)-3-oxo-3,4-dihydroquinoxaline-2-carboxamide CAS 338419-33-3
| CAS No. | 338419-33-3 |
| Molecular Formula | C22H14Cl2FN3O2 |
| Molecular Weight | 442.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(2,4-Dichlorobenzyl)-N-(4-fluorophenyl)-3-oxo-3,4-dihydroquinoxaline-2-carboxamide (C22H14Cl2FN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-(2,4-Dichlorobenzyl)-N-(4-fluorophenyl)-3-oxo-3,4-dihydroquinoxaline-2-carboxamide (CAS 338419-33-3), molecular formula C22H14Cl2FN3O2 and molecular weight 442.27 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H14Cl2FN3O2 |
| Molecular Weight | 442.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichlorobenzyl Standards
- 1-(2,6-Dichlorobenzyl)-N-(2,6-dichlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 478048-19-0)
- 1-(2,6-Dichlorobenzyl)-N-(3,5-dichlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338755-04-7)
- 1-(3,4-Dichlorobenzyl)-3-((2,6-dichlorobenzyl)oxy)-2-methylpyridin-4(1H)-one (CAS 338965-46-1)
- 5-(4-((2,4-Dichlorobenzyl)oxy)phenyl)-3-(4-methylbenzyl)-1,3,4-oxadiazol-2(3H)-one (CAS 866152-90-1)
- 1-(3,4-Dichlorobenzyl)-4-(4-fluorobenzoyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-40-2)
- 1-(2,4-Dichlorobenzyl)-6-oxo-N-(3-(trifluoromethyl)phenyl)-1,6-dihydropyridine-3-carboxamide (CAS 242797-39-3)
- 1-(2,6-Dichlorobenzyl)-2-oxo-N-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamide (CAS 338754-58-8)
- 1-(2,6-Dichlorobenzyl)-6-oxo-N-(3-(trifluoromethyl)phenyl)-1,6-dihydropyridine-3-carboxamide (CAS 339008-63-8)
Recommended Standards
- (((3,4-Dichlorophenyl)amino)(furan-2-yl)methyl)diphenylphosphine oxide (CAS 680212-11-7)
- N-(3-bromo-4-(4-methylpiperazin-1-yl)phenyl)-3-(trifluoromethyl)benzamide (CAS 477846-86-9)
- 849681-64-7 Diphenylacetylene-4,4'-diboronic acid bis(pinacol) ester MFCD16294524 4,4,5,5-tetramethyl-2-(4-{2-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethynyl}phenyl)-1,3,2-dioxaborolane (CAS 849681-64-7)
- 2,4-Dichloro-N-(4-((3-(trifluoromethyl)phenyl)thio)phenyl)benzamide (CAS 339104-99-3)
- (3,4-Dihydro-2H-benzo[b][1,4]oxazin-3-yl)methanol oxalate (CAS 1187928-27-3)
- 6-(Benzylthio)-4-(p-tolyl)-1,3,5-triazin-2(1H)-one (CAS 62460-54-2)
- (R)-1-(3,4-Dimethoxyphenyl)propan-1-amine (CAS 827004-73-9)
- 2-(3,4,5-Trimethoxyphenyl)benzo[d]oxazol-6-amine (CAS 1175899-22-5)
- 1-Methoxy-4-(1-phenylvinyl)benzene (CAS 4333-75-9)
- 3-(2-Amino-4-methylphenyl)propan-1-ol (CAS 856843-02-2)
- 6-(Methylsulfonyl)pyrimidine-2,4(1H,3H)-dione (CAS 6851-33-8)
- 3-Bromo-5-ethyl-2-hydroxybenzaldehyde (CAS 708209-58-9)
- 4,4-Dimethyl-2-imidazoline (CAS 2305-59-1)
- Cycloaspeptide A (CAS 109171-13-3)
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