3-[(E)-2-[(3-Chlorophenyl)methylidene]hydrazin-1-yl]-1,2-dihydroquinoxalin-2-one CAS 338419-74-2
| CAS No. | 338419-74-2 |
| Molecular Formula | C15H11ClN4O |
| Molecular Weight | 298.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-[(E)-2-[(3-Chlorophenyl)methylidene]hydrazin-1-yl]-1,2-dihydroquinoxalin-2-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-[(E)-2-[(3-Chlorophenyl)methylidene]hydrazin-1-yl]-1,2-dihydroquinoxalin-2-one (CAS 338419-74-2), a certified reference material (molecular formula C15H11ClN4O, MW 298.73 g/mol) for analytical method development and quality control.
The molecular framework of 3-[(E)-2-[(3-Chlorophenyl)methylidene]hydrazin-1-yl]-1,2-dihydroquinoxalin-2-one (C15H11ClN4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-[(E)-2-[(3-Chlorophenyl)methylidene]hydrazin-1-yl]-1,2-dihydroquinoxalin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11ClN4O |
| Molecular Weight | 298.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related E Standards
- N-(5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)benzimidamide (CAS 132380-89-3)
- 1-(3-Chlorophenyl)-3-(quinoxalin-6-yl)urea (CAS 672949-79-0)
- 3-[(E)-2-[(2-Chlorophenyl)methylidene]hydrazin-1-yl]-1,2-dihydroquinoxalin-2-one (CAS 338419-72-0)
- N-(2-Chlorophenyl)-N-(6-quinoxalinyl)urea (CAS 423154-67-0)
- 1-(2-Chlorophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (CAS 116572-69-1)
- 1-(2-Chlorophenyl)-5-phenyl-1h-pyrazole-4-carboxylic acid (CAS 1171970-88-9)
- 5-(4-Chlorophenyl)-1-phenyl-1H-pyrazole-3-carboxylic acid (CAS 167873-90-7)
- (1-(4-Chlorophenyl)-1H-pyrazol-4-yl)(2-hydroxyphenyl)methanone (CAS 61466-47-5)
Recommended Standards
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- Ethyl 3-(4-(ethylamino)-3-nitro-N-(pyridin-2-yl)benzamido)propanoate (CAS 1260817-88-6)
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