4-[(4-Methoxyphenyl)sulfanyl]-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline CAS 338420-56-7
| CAS No. | 338420-56-7 |
| Molecular Formula | C17H11F3N4OS |
| Molecular Weight | 376.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[(4-Methoxyphenyl)sulfanyl]-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-[(4-Methoxyphenyl)sulfanyl]-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline (CAS 338420-56-7), molecular formula C17H11F3N4OS and molecular weight 376.36 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[(4-Methoxyphenyl)sulfanyl]-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline (C17H11F3N4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-[(4-Methoxyphenyl)sulfanyl]-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H11F3N4OS |
| Molecular Weight | 376.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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