4-[4-Chloro-2-(trifluoromethyl)phenyl]thiomorpholine-3,5-dione CAS 338421-37-7
| CAS No. | 338421-37-7 |
| Molecular Formula | C11H7ClF3NO2S |
| Molecular Weight | 309.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-[4-Chloro-2-(trifluoromethyl)phenyl]thiomorpholine-3,5-dione (CAS 338421-37-7), molecular formula C11H7ClF3NO2S and molecular weight 309.69 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-[4-Chloro-2-(trifluoromethyl)phenyl]thiomorpholine-3,5-dione is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 309.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-[4-Chloro-2-(trifluoromethyl)phenyl]thiomorpholine-3,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7ClF3NO2S |
| Molecular Weight | 309.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- 2-Chloro-N-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl)benzamide (CAS 477885-65-7)
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- 3-Chloro-N-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl)benzamide (CAS 477885-68-0)
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Recommended Standards
- 2,2,2-trifluoroethyl N-(3-chloro-1-benzothiophen-2-yl)carbamate (CAS 1311313-98-0)
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- 2-(4-Chlorophenyl)naphtho[2,3-d]oxazole-4,9-dione (CAS 192718-11-9)
- 5-fluoro-2-nitrophenyl 4-(chloromethyl)benzoate (CAS 219500-20-6)
- 4-amino-3-(2-methoxyethyl)phenol (CAS 161368-65-6)
- 8-Chloro-2,2-dimethylchroman-6-carbaldehyde (CAS 1350761-35-1)
- 1039989-87-1 (3-Isopropylphenyl)propylamine MFCD09753304 (CAS 1039989-87-1)
- Tert-butyl 4-(3-methoxy-2-methyl-3-oxopropyl)piperazine-1-carboxylate (CAS 886366-38-7)
- Dimethyl (2-oxoethyl)phosphonate (CAS 10038-65-0)
- 1-Ethoxy-4-(prop-2-yn-1-yloxy)benzene (CAS 5651-84-3)
- 4-chloroanthracene-9-carboxylic acid (CAS 2713428-82-9)
- 4,6-Diethyl-2-oxo-2H-chromene-3-carbonitrile (CAS 1352515-17-3)
- 5-Methoxyspiro[indoline-3,4'-piperidin]-2-one hydrochloride (CAS 1779125-38-0)
- Liraglutide(10-22)TFA Salt (CAS CATO-C4X-199211)
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