N-(4-chlorophenyl)-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide CAS 338423-96-4
| CAS No. | 338423-96-4 |
| Molecular Formula | C16H16ClNO4S |
| Molecular Weight | 353.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-chlorophenyl)-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide.
N-(4-chlorophenyl)-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide (CAS 338423-96-4), molecular formula C16H16ClNO4S and molecular weight 353.82 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C16H16ClNO4S, N-(4-chlorophenyl)-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 353.82 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(4-chlorophenyl)-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16ClNO4S |
| Molecular Weight | 353.82 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- N-(4-chloro-2-methylphenyl)-N-tosylglycine (CAS 425414-88-6)
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- N-(3-chloro-4-methylphenyl)-N-tosylglycine (CAS 592470-83-2)
- N-Benzyl-4-chloro-N-hydrazinocarbonylmethyl-benzenesulfonamide (CAS 333319-70-3)
- 2-{7-chloro-1H-pyrazolo[4,3-d]pyrimidin-5-yl}ethan-1-amine (CAS 1211532-55-6)
- 6-Chloro-4-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 929974-08-3)
- 2,2-Difluoro-2-(1-hydroxycyclohexyl)acetic acid (CAS 206346-77-2)
- 1215530-49-6 4-[6-(Trifluoromethyl)pyridazin-3-yl]morpholine (CAS 1215530-49-6)
- 3-Propoxy-1-(tetrahydrofuran-3-yl)but-3-en-2-amine (CAS 1255237-45-6)
- 3,5-Difluoro-4-(4-fluorophenoxy)aniline (CAS 549547-31-1)
- 2-Cyclobutyl-2-propanol (CAS 59383-67-4)
- b-Nicotinic Acid Mononucleotide (CAS 321-02-8)
- 3,4-Dibromo-2-nitrothiophene (CAS 35633-91-1)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
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