2-[4-(4-Nitrophenyl)piperazin-1-yl]ethyl N-[3-(trifluoromethyl)phenyl]carbamate CAS 338748-63-3
| CAS No. | 338748-63-3 |
| Molecular Formula | C20H21F3N4O4 |
| Molecular Weight | 438.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-[4-(4-Nitrophenyl)piperazin-1-yl]ethyl N-[3-(trifluoromethyl)phenyl]carbamate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-[4-(4-Nitrophenyl)piperazin-1-yl]ethyl N-[3-(trifluoromethyl)phenyl]carbamate (CAS 338748-63-3), molecular formula C20H21F3N4O4 and molecular weight 438.40 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-[4-(4-Nitrophenyl)piperazin-1-yl]ethyl N-[3-(trifluoromethyl)phenyl]carbamate (C20H21F3N4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 438.40 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[4-(4-Nitrophenyl)piperazin-1-yl]ethyl N-[3-(trifluoromethyl)phenyl]carbamate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H21F3N4O4 |
| Molecular Weight | 438.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Nitrophenyl Standards
- (3E)-3-[2-(4-Nitrophenyl)hydrazin-1-ylidene]-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-2-one (CAS 303984-87-4)
- 4-Nitrophenyl ((benzyloxy)carbonyl)-L-tyrosinate (CAS 3556-56-7)
- N-(5-((4-Nitrophenyl)sulfonyl)thiazol-2-yl)-2-(phenylthio)acetamide (CAS 797019-58-0)
- N-(3-Nitrophenyl)-2-(4-((2-(4-nitrophenyl)hydrazono)methyl)phenoxy)acetamide (CAS 331962-97-1)
- 3,7-Bis(4-nitrophenyl)-10H-phenothiazine (CAS 1620912-35-7)
- 4-(3-Nitrophenyl)-2-dimethoxymethyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 5-Isopropyl Ester 3-Methyl Ester (CAS 75530-94-8)
- 4-Nitrophenyl 2-(3-(trifluoromethyl)phenyl)-7-azaspiro[3.5]Nonane-7-carboxylate (CAS 1225276-30-1)
- 2-((3-Nitrophenyl)sulfonyl)ethyl 3-(chlorosulfonyl)benzoate (CAS 651728-08-4)
Recommended Standards
- 2-(3-Phenyl-1H-indole-2-carbonyl)-N-(3-(trifluoromethyl)phenyl)hydrazine-1-carboxamide (CAS 338415-08-0)
- 5,6-Dimethoxy-3-(2,2,2-trifluoroacetamido)-2,3-dihydro-1H-inden-1-yl p-tolylcarbamate (CAS 866131-55-7)
- (4Z)-2-{[(4-bromophenyl)carbamoyl]methyl}tetradec-4-enoic acid (CAS 1025274-31-0)
- N-(3-(Dipropylamino)phenyl)acetamide (CAS 51732-34-4)
- 5-Fluoro-2-(piperidin-4-yloxy)pyrimidine hydrochloride (CAS 950648-97-2)
- tert-Butyl (6-chloro-3-iodopyridin-2-yl)carbamate (CAS 1622407-12-8)
- 3-(Hydroxymethyl)-7-methoxy-1-methylquinolin-2(1H)-one (CAS 924769-60-8)
- 5-fluorofuran-2-carbaldehyde (CAS 50899-04-2)
- n-(4-Fluorophenyl)-1,2,3,4-tetrahydroquinoline-2-carboxamide (CAS 1103212-50-5)
- 3-4-6-Tri-O-benzyl-2-deoxy-D-glucopyranose (CAS 132732-60-6)
- Methyl 6-hydroxy-7-(2-methylallyl)-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylate (CAS 866393-53-5)
- 1-(6-Chloropyrimidin-4-yl)piperidin-4-amine (CAS 773052-63-4)
- 2-Formyl-N,N-dimethyl-1H-imidazole-1-sulfonamide (CAS 167704-98-5)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
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