(2E)-3-{[(4-methylphenyl)methyl]amino}-N-[3-(trifluoromethyl)phenyl]but-2-enamide CAS 338748-79-1
| CAS No. | 338748-79-1 |
| Molecular Formula | C19H19F3N2O |
| Molecular Weight | 348.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (2E)-3-{[(4-methylphenyl)methyl]amino}-N-[3-(trifluoromethyl)phenyl]but-2-enamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 348.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies (2E)-3-{[(4-methylphenyl)methyl]amino}-N-[3-(trifluoromethyl)phenyl]but-2-enamide (CAS 338748-79-1), a certified reference material (molecular formula C19H19F3N2O, MW 348.36 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H19F3N2O |
| Molecular Weight | 348.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- 2-[5-Methyl-3-(4-methylphenyl)-7-oxo-7H-furo[3,2-g]chromen-6-yl]acetic acid (CAS 853892-67-8)
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Recommended Standards
- 6-(2-Oxo-2H-chromen-3-yl)imidazo[2,1-b][1,3,4]thiadiazole-2-sulfonamide (CAS 183999-59-9)
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- Lomitapide M1 (CAS 182439-41-4)
- (E)-N'-(1-(Thiophen-2-yl)ethylidene)-2-(trifluoromethyl)benzenesulfonohydrazide (CAS 2553409-18-8)
- 3-(4-Bromo-3-methylphenyl)-5-methylisoxazole-4-carboxylic acid (CAS 1500083-83-9)
- 2-Ethyl-1-methyl-5-nitro-1H-benzo[d]imidazole (CAS 286837-93-2)
- 3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,5-dichlorophenyl)propanoic acid (CAS 188814-26-8)
- 2-(4-(4-Fluorophenyl)-2-methylthiazol-5-yl)acetic acid 568543-71-5 8325AB C12H10FNO2S (CAS 568543-71-5)
- Clenbuterol Impurity 15 (CAS 38339-14-9)
- 1242994-98-4 Ethyl 3-amino-4-[(2-{[(ethylamino)carbonyl]amino}ethyl)amino]benzoate MFCD15732369 (CAS 1242994-98-4)
- 2-Amino-5-chloro-4-iodophenol (CAS 1037298-24-0)
- Methyl (2E)-3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-2-(4-fluorobenzenesulfonyl)prop-2-enoate (CAS 1327178-53-9)
- Zolmitriptan-d6 (CAS 1217644-84-2)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
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