4-(4-Fluorophenyl)-N-(5-iodopyridin-2-yl)thiazol-2-amine CAS 338748-98-4
| CAS No. | 338748-98-4 |
| Molecular Formula | C14H9FIN3S |
| Molecular Weight | 397.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(4-Fluorophenyl)-N-(5-iodopyridin-2-yl)thiazol-2-amine (C14H9FIN3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-(4-Fluorophenyl)-N-(5-iodopyridin-2-yl)thiazol-2-amine (CAS 338748-98-4), a certified reference material (molecular formula C14H9FIN3S, MW 397.21 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-Fluorophenyl)-N-(5-iodopyridin-2-yl)thiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9FIN3S |
| Molecular Weight | 397.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 1-(4-fluorophenyl)-3-[(2,3,5,6-tetrachloro-4-pyridyl)thio]prop-2-en-1-one (CAS 299462-32-1)
- 2-((1-(2-Fluorophenyl)-1H-tetrazol-5-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 838883-92-4)
- 2-(4-(4-Fluorophenyl)piperazin-1-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 161290-83-1)
- N-(2-((3-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)oxy)ethyl)-2-(thiophen-2-yl)acetamide (CAS 1021098-47-4)
- 3-(4-Fluorophenyl)-5-(4-methoxybenzyl)-8-methyl-5H-pyrazolo[4,3-c]quinoline (CAS 866345-17-7)
- 2-((5-(3-(4-Fluorophenyl)ureido)-1,3,4-thiadiazol-2-yl)thio)-N,N-dimethyl-3-oxobutanamide (CAS 886937-50-4)
- 5-(4-Fluorophenyl)-2-(methylsulfanyl)-6-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 866019-70-7)
- 3-Benzyl-1-(2-{[(4-fluorophenyl)methyl]sulfanyl}-2-methylpropyl)-4-hydroxy-1,2-dihydropyridin-2-one (CAS 477869-86-6)
Recommended Standards
- 2-(2,6-Dichlorophenyl)-1H-imidazo[4,5-b]phenazine 5,10-dioxide (CAS 303059-20-3)
- 5'-Bromo-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid (CAS 1250980-10-9)
- 4-(Benzyloxy)-3-ethoxy-5-iodobenzamide (CAS 1706455-52-8)
- Prop-2-yn-1-yl 3-chloro-4-((2-chloro-4-fluorobenzyl)oxy)-5-ethoxybenzoate (CAS 1706452-94-9)
- 4-[[(4-Phenyl-1-piperazinyl)imino]methyl]-1,3-benzenediol (CAS 1685252-72-5)
- (5-Methylbenzo[b]thiophen-3-yl)boronic acid (CAS 1194254-39-1)
- Ethyl 3-(3-(2-chloroethyl)ureido)benzoate (CAS 803729-93-3)
- (E)-3-(1-ethyl-5-methyl-1H-pyrazol-4-yl)acrylic acid (CAS 512809-25-5)
- Cyclopentyl trifluoromethanesulfonate (CAS 131929-89-0)
- (2,5-Difluorophenyl)(phenyl)methanone (CAS 85068-36-6)
- 5H-Oxazolo[3,2-a]pyridin-5-ol (CAS 201532-30-1)
- 4-((6-Chloropyridin-3-yl)sulfonyl)morpholine (CAS 52480-33-8)
- 3-(3-(Dipropylcarbamoyl)-1h-pyrazol-1-yl)propanoic acid (CAS 1006435-43-3)
- Liraglutide(10-22)TFA Salt (CAS CATO-C4X-199211)
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