2-(2,4-Difluorophenoxy)-4-methylquinoline CAS 338749-98-7
| CAS No. | 338749-98-7 |
| Molecular Formula | C16H11F2NO |
| Molecular Weight | 271.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(2,4-Difluorophenoxy)-4-methylquinoline (CAS 338749-98-7), molecular formula C16H11F2NO and molecular weight 271.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2,4-Difluorophenoxy)-4-methylquinoline (C16H11F2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2,4-Difluorophenoxy)-4-methylquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11F2NO |
| Molecular Weight | 271.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenoxy Standards
- 5-(1-(2,4-Difluorophenoxy)ethyl)-4-methyl-4H-1,2,4-triazole-3-thiol (CAS 861409-17-8)
- 3-(2,4-Difluorophenoxy)propane-1-sulfonyl chloride (CAS 1340339-43-6)
- 3-(3,4-Difluorophenoxy)propane-1-sulfonyl chloride (CAS 1342357-95-2)
- 3-(2,3-Difluorophenoxy)propane-1-sulfonyl chloride (CAS 1407260-25-6)
- 3-(2,5-Difluorophenoxy)propane-1-sulfonyl chloride (CAS 1481650-26-3)
- 2-(2,3-Difluorophenoxy)-1-(piperazin-1-yl)propan-1-one (CAS 1271613-34-3)
- 3-(4-(2,4-Difluorophenoxy)phenyl)-1H-pyrazole (CAS 861213-56-1)
- 4-((2,4-Difluorophenoxy)methyl)-5-methylisoxazole-3-carboxylic acid (CAS 932918-49-5)
Recommended Standards
- 2-((Difluoromethyl)sulfonyl)benzenesulfonamide (CAS 63647-66-5)
- 2-(Difluoromethyl)-1-phenylquinolin-4(1H)-one (CAS 837364-34-8)
- 2-((4-(Trifluoromethyl)pyrimidin-2-yl)thio)aniline (CAS 680593-98-0)
- 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one (CAS 663615-45-0)
- Bis(2-chloroethyl) 2-chloroethylphosphonate (CAS 6294-34-4)
- 3-(4-Methoxyphenyl)-N-(4-((4-methylpiperazin-1-yl)methyl)phenyl)propanamide (CAS 2335560-70-6)
- (4-Amino-2-(difluoromethyl)pyridin-3-yl)methanol (CAS 1803693-96-0)
- 7-Fluoro-2H-benzo[b][1,4]thiazin-3(4H)-one (CAS 100638-20-8)
- 3-Chloroaniline Hydrochloride (CAS 141-85-5)
- (R)-2-((1-Benzylpyrrolidin-3-yl)(ethyl)amino)acetic acid (CAS 1353996-35-6)
- 3-(2-Benzylpiperazin-1-yl)propanoic acid (CAS 1060814-18-7)
- 2,3-Dimethyl-4-thiocyanatophenol (CAS 6186-84-1)
- 5-(chlorosulfonyl)-2,3-dimethoxybenzoic acid (CAS 74651-62-0)
- Semaglutide impurity 248 (CAS CATO-C4X-2226248)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com