(4Z)-1-(4-Chlorophenyl)-3-ethoxy-4-{[(4-methylphenyl)amino]methylidene}-4,5-dihydro-1H-pyrazol-5-one CAS 338751-07-8
| CAS No. | 338751-07-8 |
| Molecular Formula | C19H18ClN3O2 |
| Molecular Weight | 355.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (4Z)-1-(4-Chlorophenyl)-3-ethoxy-4-{[(4-methylphenyl)amino]methylidene}-4,5-dihydro-1H-pyrazol-5-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (4Z)-1-(4-Chlorophenyl)-3-ethoxy-4-{[(4-methylphenyl)amino]methylidene}-4,5-dihydro-1H-pyrazol-5-one (CAS 338751-07-8), a certified reference material (molecular formula C19H18ClN3O2, MW 355.82 g/mol) for analytical method development and quality control.
The molecular framework of (4Z)-1-(4-Chlorophenyl)-3-ethoxy-4-{[(4-methylphenyl)amino]methylidene}-4,5-dihydro-1H-pyrazol-5-one (C19H18ClN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (4Z)-1-(4-Chlorophenyl)-3-ethoxy-4-{[(4-methylphenyl)amino]methylidene}-4,5-dihydro-1H-pyrazol-5-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H18ClN3O2 |
| Molecular Weight | 355.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Z Standards
- 3-((4-(2-((3-Chlorophenyl)amino)pyrimidin-4-yl)pyridin-2-yl)amino)propan-1-ol (CAS 164658-13-3)
- 3-(2-Chlorophenyl)-N-(4-(dimethylamino)phenyl)-5-methylisoxazole-4-carboxamide (CAS 349133-59-1)
- 3-(4-Chlorophenyl)-7-(naphthalen-2-yl)pyrazolo[1,5-a]pyrimidine (CAS 866049-92-5)
- 4-(3-Chlorophenyl)-6-methyl-2-oxo-N-(o-tolyl)-1,2,3,4-tetrahydropyrimidine-5-carboxamide (CAS 332373-23-6)
- 2-(4-Chlorophenyl)-2-oxoethyl 4-(1H-indol-3-yl)butanoate (CAS 860650-72-2)
- 3-(5-(3-Chlorophenyl)furan-2-yl)-N-(3-methoxyphenyl)propanamide (CAS 853312-53-5)
- 3-[(4-Chlorophenyl)methyl]-4-hydroxy-1-[(3-methoxyphenyl)methyl]-1,2-dihydropyridin-2-one (CAS 477846-44-9)
- 5-(4-Chlorophenyl)-N-(2-methoxybenzyl)-2-methylfuran-3-carboxamide (CAS 941238-56-8)
Recommended Standards
- 1-(4-Chloro-7-methoxyquinolin-2-yl)-3-(2,6-dimethylphenyl)urea (CAS 196875-45-3)
- (4Z)-4-{[(5-chloro-2-hydroxyphenyl)amino]methylidene}-1-(3,4-dimethylphenyl)-3-methyl-4,5-dihydro-1h-pyrazol-5-one (CAS 310456-09-8)
- 1-(2-Chloro-6-(1H-1,2,4-triazol-1-yl)benzyl)-3-(2,6-dimethylphenyl)urea (CAS 866042-59-3)
- (S)-8-(1-((6-Chloropyrimidin-4-yl)amino)propan-2-yl)-N-methylquinoline-4-carboxamide (CAS 1476076-42-2)
- Potassium (4-aminophenyl)trifluoroborate (CAS 1386231-56-6)
- 2-(4-Tolyl)-4-(2-hydroxyphenyl)thiazole (CAS 1965305-04-7)
- Mogroside III-A2 (CAS 88901-43-3)
- 2-(Hydroxymethyl)-2-methyl-1,3-epoxypropane 3-(Hydroxymethyl)-3-methyloxetane 3-Methyl-3-oxetanemethanol 3143-02-0 M1136 (CAS 3143-02-0)
- alpha-Ethenylbenzylamine (CAS 4393-21-9)
- 4-(5-(Pyrrolidin-1-ylmethyl)furan-2-yl)aniline (CAS 89249-99-0)
- 2-Methyl-5-(1H-pyrazol-5-yl)furan-3-sulfonyl chloride (CAS 1350521-53-7)
- 5-Oxo-1-(2-pyridinylmethyl)-3-pyrrolidinecarboxylic acid (CAS 845546-25-0)
- 4-[5-(oxolan-2-yl)-1,2,4-oxadiazol-3-yl]phenol (CAS 1152506-99-4)
- (Tyr9)-Cholecystokinin Octapeptide (sulfated) (H-9770.0005) (CAS 96607-61-3)
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