2-(4-Chlorophenyl)-5-ethoxy-4-(((4-hydroxyphenyl)imino)methyl)-1,2-dihydro-3H-pyrazol-3-one CAS 338751-23-8

Purity 97%+In StockPharmaceutical Standards
CAS No.338751-23-8
Molecular FormulaC18H16ClN3O3
Molecular Weight357.79 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4-Chlorophenyl)-5-ethoxy-4-(((4-hydroxyphenyl)imino)methyl)-1,2-dihydro-3H-pyrazol-3-one CAS 338751-23-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Chlorophenyl)-5-ethoxy-4-(((4-hydroxyphenyl)imino)methyl)-1,2-dihydro-3H-pyrazol-3-one.

2-(4-Chlorophenyl)-5-ethoxy-4-(((4-hydroxyphenyl)imino)methyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 338751-23-8) is a high-purity analytical reference standard with the molecular formula C18H16ClN3O3 and a molecular weight of 357.79 g/mol.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-(4-Chlorophenyl)-5-ethoxy-4-(((4-hydroxyphenyl)imino)methyl)-1,2-dihydro-3H-pyrazol-3-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 357.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H16ClN3O3
Molecular Weight357.79 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms3

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